Indistinguishable mitochondrial phenotypes after exposure of healthy myoblasts to myalgic encephalomyelitis or control serum, 2026, Ryback et al

How does this compare to the Mughal et al. (2025) paper showing changes in skeletal muscle after incubation with ME and LC sera?
What accounts for the differing results?

pubmed.ncbi.nlm.nih.gov

Metabolic adaptation and fragility in healthy 3D in vitro skeletal muscle tissues exposed to chronic fatigue syndrome and Long COVID-19 sera - PubMed

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long Covid-19 (LC-19) are complex conditions with no diagnostic markers or consensus on disease progression. Despite extensive research, no<i>in vitro</i>model exists to study skeletal muscle wasting, peripheral weakness, or...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
 
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