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IBS: Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917

Discussion in 'Health News and Research unrelated to ME/CFS' started by Cheshire, Nov 6, 2017.

  1. Cheshire

    Cheshire Senior Member (Voting Rights)

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    Teresa Pérez-Berezo, Julien Pujo, Patricia Martin, Pauline Le Faouder, Jean-Marie Galano, Alexandre Guy, Claude Knauf, Jean Claude Tabet, Sophie Tronnet, Frederick Barreau, Maud Heuillet, Gilles Dietrich, Justine Bertrand-Michel, Thierry Durand, Eric Oswald & Nicolas Cenac

    https://www.nature.com/articles/s41467-017-01403-9
     
  2. adreno

    adreno Senior Member (Voting Rights)

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    This probiotic is also known as Mutaflor. I have had good improvements with this one; might post more about this later.
     
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  3. Skippa

    Skippa Senior Member (Voting Rights)

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    Yes please i'd love to know, and about sources (if it isn't readily available) :)
     
  4. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    You can purchase Mutaflor in Canada, Germany, Finland, and Australia.
     
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  5. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    I'm still debating whether or not to try this probiotic. I've spent so much money over the years on products that haven't worked, but this is one of the probiotics that Ken Lassesen of CFS Remission recommends for ME. And it is available for sale here in Canada which is a bonus.
     
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  6. adreno

    adreno Senior Member (Voting Rights)

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    I'm pretty sure I moved from moderate to mild because of this one.
     
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  7. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    That's good to know. I think in the New Year I'll probably go ahead and order some and see how it goes. There is another one with e-coli that Ken also recommends but I believe it is only available from Europe so I don't know whether or not it will allowed it into Canada.
     
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  8. adreno

    adreno Senior Member (Voting Rights)

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    Just a note; the first two weeks were absolutely awful and all my symptoms seemed intensified. Then it got better. Probably a phase of LPS from some bacteria getting crowded out and dying off.
     
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  9. Snowdrop

    Snowdrop Senior Member (Voting Rights)

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    @adreno

    Can you describe your use of Mutaflor; what dose you used and how long before symptoms abated and what type of symptoms if you don't mind sharing? I'd be interested.

    ETA: didn't see above post.
     
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  10. TigerLilea

    TigerLilea Senior Member (Voting Rights)

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    @adreno How long have you been using Mutaflor for and do you take breaks from it the way that Ken Lassesen suggests?
     
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  11. adreno

    adreno Senior Member (Voting Rights)

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    About 3 months? I took it daily the first few weeks, but now I just take it once in a while. It seems to have colonized.
     
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  12. adreno

    adreno Senior Member (Voting Rights)

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    Just one capsule daily. Every symptom got worse at first, including OI, muscle fatigue and pain, headache, etc. Took a few weeks to get over it.
     
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