High Prevalence and Clinical Impact of Fibromyalgia in Functional Motor Disorder 2026 Serranova et al

Andy

Senior Member (Voting rights)
Abstract

Background

Fibromyalgia is characterized by widespread pain, fatigue, sleep and cognitive symptoms. It overlaps clinically with functional motor disorder (FMD), yet its prevalence and impact in FMD remain uncertain.

Objective

To determine the prevalence of fibromyalgia in FMD using the current criteria and evaluate its effects on motor symptoms and health-related quality of life (HRQoL).

Methods

A total of 138 consecutive FMD patients completed the Fibromyalgia Survey Questionnaire, subjective motor ratings and HRQoL measures. Motor impairment was assessed using the Simplified FMD Rating Scale, and physical/psychiatric comorbidities and medication use were recorded.

Results

Fibromyalgia was present in 44.9% of patients (95% CI: 36.5–53.6%). Those with fibromyalgia had more severe motor symptoms, lower HRQoL and greater medication use. Higher fibromyalgia severity, S-FMDRS, and psychiatric comorbidity were independent predictors of lower HRQoL.

Conclusions

Fibromyalgia is common in FMD and associated with worse clinical outcomes, supporting systematic screening and integrated management.

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