Hidden gut cells could transform food allergy treatment

Mij

Senior Member (Voting Rights)
A hidden gut pathway could transform how we prevent deadly food allergy reactions

Date: September 8, 2025

Source: Arizona State University

Summary: Scientists have uncovered a surprising new pathway behind life-threatening food allergies. Instead of histamine, a different chemical called leukotrienes drives severe reactions in the gut. These molecules, released by specialized mast cells, trigger inflammation and anaphylaxis when food allergens are ingested. Drugs already approved for asthma may block this pathway, opening the door to new ways to prevent or treat food-induced allergic emergencies.
 
Interesting. My food intolerances aren't histamine reactions, but they worsen my ME symptoms, so maybe this is the pathway.
 
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