Genetics: NEGR1

forestglip said:
I haven't really been able to follow what exactly you're doing. Maybe you could lay out your overarching plan, and maybe describe what everything in one row of the table on this webpage means?
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Will try to give a fuller writeup a go some other time when I’m up to it. But it’s basically just GenHancer info on promoters and enhancers (see the Genomics section on a GeneCards page) for DecodeME genes with links to view the locations on the DecodeME LocusZoom to see if they’re relevant.
 
hotblack said:
But it’s basically just GenHancer info on promoters and enhancers (see the Genomics section on a GeneCards page) for DecodeME genes with links to view the locations on the DecodeME LocusZoom to see if they’re relevant.
Click to expand...
Ah, ok, so the idea is, if there are significant hits near a gene, plus significant hits near multiple enhancers or promoters which encourage expression of that gene, it might be more likely to be relevant.

I just brushed up on the basics of what promoters and enhancers are with this video: Promoters and Enhancers
 
forestglip said:
Ah, ok, so the idea is, if there are significant hits near a gene, plus significant hits near multiple enhancers or promoters which encourage expression of that gene, it might be more likely to be relevant.

I just brushed up on the basics of what promoters and enhancers are with this video: Promoters and Enhancers
Click to expand...
Yeah, it was meant to be a quick ‘oh this info on regulatory elements looks interesting, I wonder if I can knock something up to make it easy to link to and check if there are correlations to changes in the DecodeME data for the candidate genes, maybe it will tell us something’. And then got more complicated…
 
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