Review ENDOTEXT: CHRONIC FATIGUE SYNDROME, 2023, Lim & Torpy

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Dolphin

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https://www.endotext.org/wp-content/uploads/pdfs/chronic-fatigue-syndrome.pdf

CHRONIC FATIGUE SYNDROME

WT Lim, Endocrine and Metabolic Unit, Royal Adelaide Hospital, North Terrace, Adelaide SA 5000. Alexlim.1992@gmail.com

DJ Torpy, MBBS, PhD, FRACP, Endocrinologist, Endocrine and Metabolic Unit, Royal Adelaide Hospital, North Terrace, Adelaide SA 5000. David.torpy@sa.gov.au

Updated August 14, 2023

ABSTRACT

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is an enigmatic medical condition that has growing prevalence across the globe, often diagnosed after exclusion of other medical or mental illnesses.

As there is no clinical test to confirm the presence of this condition, the diagnosis is syndromic based on different clinical definitions.

There was mixed evidence to support the use of a specific therapy that provides palliative effect.

Pathophysiological hypotheses can be categorized into infection, immune, mitochondrial, neurobehavioral, or stress system (HPA axis and sympathetic nervous system) disorders.

The prognosis of ME/CFS is mixed but recovery does occur in many cases, over time.

All-cause mortality rate is not increased.
 
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That's a bit of a depressing read. It sort of gets some things right, but not quite.

Cognitive behavioral therapy involves the provision of information and counselling to reduce the psychological impediments to recovery, as well as encouraging the patient to participate at an appropriate level of social and occupational activity. It is important for clinicians to establish a rapport as patients may be mistrustful due to prior negative health care experiences (99). In randomized- controlled trials comparing CBT to control conditions, the intervention has been shown to have a positive overall effect (21). Graded-exercise therapy may also be of benefit (22).
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As you would expect from a resource for endocrinologists, there is a big emphasis on issues to do with cortisol and the HPA axis.

It would be possible to address the many issues in this resource, but it would take quite a while and there's no guarantee that ENDOTEXT would be interested in engaging. I guess a question is, 'how influential is ENDOTEXT'? Maybe it would be more productive and useful to publish a good review of the evidence around cortisol in ME/CFS.
 
Cognitive behavioral therapy involves the provision of information and counselling to reduce the psychological impediments to recovery, as well as encouraging the patient to participate at an appropriate level of social and occupational activity.

Because we are such incompetent fools with no idea how to engage in "an appropriate level of social and occupational activity" that we need to be 'trained' by experts who have no idea what they are dealing with nor how to deal with it.
 
Hutan said:
That's a bit of a depressing read. It sort of gets some things right, but not quite.



As you would expect from a resource for endocrinologists, there is a big emphasis on issues to do with cortisol and the HPA axis.

It would be possible to address the many issues in this resource, but it would take quite a while and there's no guarantee that ENDOTEXT would be interested in engaging. I guess a question is, 'how influential is ENDOTEXT'? Maybe it would be more productive and useful to publish a good review of the evidence around cortisol in ME/CFS.
Click to expand...
I hope for someone's sake that the text you quoted was written by a LLM because even then it would have to be a pretty bad one and that's just embarrassing. Reads like someone imitating human language and failing badly at it.
 
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