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Effects of a Green Oat Herb Extract on Cognitive Performance and Neurophysiological Activity: A Randomized Double-Blind Study, Horta, 2021

Discussion in 'Other health news and research' started by Jaybee00, Nov 17, 2021.

  1. Jaybee00

    Jaybee00 Senior Member (Voting Rights)

    Messages:
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    https://www.frontiersin.org/articles/10.3389/fnins.2021.748188/full


    Effects of a Green Oat Herb Extract on Cognitive Performance and Neurophysiological Activity: A Randomized Double-Blind Placebo-Controlled Study


    Green oat extracts have been used for centuries in traditional medicine in view of their supposed beneficial effects on cognition and mood. Recently, a specific green oat formulation (Neuravena®) showed to have significant bioactive compounds potentially associated with the enhancement of processing speed, working memory and attention. The main aim of the current study was to compare the potential effect of acute administration of 800 mg of Neuravena® with placebo on a set of neurophysiological correlates of processing speed, attention, performance-monitoring and inhibitory control. Twenty healthy participants were randomized to receive either Neuravena®or placebo. Electroencephalographic (EEG) signal acquisition was obtained while participants carried out the modified Eriksen flanker and oddball tasks. Both groups were compared on measures of behavioral task performance, and a set of event-related potentials (ERPs) components related to performance monitoring (the error-related negativity; ERN and the N2), target detection, and attention (P3a/P3b). Following active-intervention N2, ERN, and P3a/P3b were significantly reduced and performance was faster, with no loss of accuracy. Conversely, no neurophysiological differences were found in the placebo group before and after treatment and performance worsened significantly in terms of reaction time and accuracy. Acute administration of 800 mg of Neuravena® appears to enhance the optimization of neural resources and positively influences cognitive performance in tasks associated with executive functions, processing speed and attention. Moreover, Neuravena® prevents the deleterious effects of tiredness during task performance.

    Company sponsored research
     
    Peter Trewhitt likes this.
  2. Jaybee00

    Jaybee00 Senior Member (Voting Rights)

    Messages:
    1,063
    Also this one

    https://www.mdpi.com/2072-6643/12/6/1598/htm


    Acute and Chronic Effects of Green Oat (Avena sativa) Extract on Cognitive Function and Mood during a Laboratory Stressor in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled Study in Healthy Humans

    Green oat (Avena sativa) extracts contain several groups of potentially psychoactive phytochemicals. Previous research has demonstrated improvements in cognitive function following a single dose of these extracts, but not following chronic supplementation. Additionally, whilst green oat extracts contain phytochemicals that may improve mood or protect against stress, for instance species-specific triterpene saponins, to date this possibility has not been examined. The current study investigated the effects of a single dose and four weeks of administration of a novel, Avena sativa herbal extract (cognitaven®) on cognitive function and mood, and changes in psychological state during a laboratory stressor. The study adopted a dose-ranging, double-blind, randomised, parallel groups design in which 132 healthy males and females (35 to 65 years) received either 430 mg, 860 mg, 1290 mg green oat extract or placebo for 29 days. Assessments of cognitive function, mood and changes in psychological state during a laboratory stressor (Observed Multitasking Stressor) were undertaken pre-dose and at 2 h and 4 h post-dose on the first (Day 1) and last days (Day 29) of supplementation. The results showed that both a single dose of 1290 mg and, to a greater extent, supplementation for four weeks with both 430 mg and 1290 mg green oat extract resulted in significantly improved performance on a computerised version of the Corsi Blocks working memory task and a multitasking task (verbal serial subtractions and computerised tracking) in comparison to placebo. After four weeks, the highest dose also decreased the physiological response to the stressor in terms of electrodermal activity. There were no treatment-related effects on mood. These results confirm the acute cognitive effects of Avena sativaextracts and are the first to demonstrate that chronic supplementation can benefit cognitive function and modulate the physiological response to a stressor.




     
    Peter Trewhitt likes this.
  3. Peter Trewhitt

    Peter Trewhitt Senior Member (Voting Rights)

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    2,692
    This phase alone, without brain scan evidence, is pseudoscientific advertising propaganda.
     
  4. hibiscuswahine

    hibiscuswahine Senior Member (Voting Rights)

    Messages:
    285
    Location:
    Aotearoa/New Zealand
    https://en.wikipedia.org/wiki/Electrodermal_activity, “More recent research and additional electrochemical skin conductance, (sometimes responsive and sometimes apparently spontaneous) suggest that EDA is more complex than it seems, and research continues into the source and significance of EDA”, Scientology uses a modified EDA machine.
     
    Peter Trewhitt likes this.

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