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Review Effectiveness and tolerance of exercise interventions for long COVID: a systematic review of randomised controlled trials, 2025, McDowell et al

Discussion in 'Long Covid research' started by Sly Saint, Mar 24, 2025.

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  1. ME/CFS Skeptic

    ME/CFS Skeptic Senior Member (Voting Rights)

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    Don't quite understand what you mean by this? Isn't the problem simply that these trials did not include a non-exercise control group (and thus cannot estimate the effect of exercise)?
     
    ME/CFS Skeptic, Mar 25, 2025
    #21
    Peter Trewhitt likes this.
  2. ME/CFS Skeptic

    ME/CFS Skeptic Senior Member (Voting Rights)

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    Looked at some of these studies like Li 2022 or Romanet 2023 and they focused on patients discharged from hospital with pulmonary problems so quite different from the ME/CFS subtype of Long Covid.
     
    ME/CFS Skeptic, Mar 25, 2025
    #22
    Peter Trewhitt and Trish like this.
  3. rvallee

    rvallee Senior Member (Voting Rights)

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    Haven't really kept track of the many published on the forum alone. There are easily dozens.
     
    rvallee, Mar 25, 2025
    #23
    Peter Trewhitt likes this.
  4. Hutan

    Hutan Moderator Staff Member

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    Well, yes. But it is even worse than that.

    J-A: Exercise vs leaflet
    J-A: Exercise vs leaflet
    Li: Telerehab vs brief instructions at baseline
    Okan: Exercise vs brochure
    R-B: Telerehab vs nothing
    Romanet: Supervised exercise vs physiotherapy
    Rutkowski: Virtual reality exercise vs supervised exercise
    Vallier: In hospital rehab including exercise vs home based rehab including exercise

    Because not only do some of the trials not have a non-exercise control group, but the controls in some of the trials are the same as the treatments in some of the others.

    For example, for Rutkowski, they studied exercise using virtual reality versus supervised exercise. For Vallier, the control was home-based rehab including exercise, but in other studies (Li and R-B), the active treatment was home-based exercise.

    The studies did all sorts of things, and for as little as 2 or 3 weeks in some, and the review just combined the effects all together.
     
    Hutan, Mar 26, 2025
    #24
    rvallee, shak8, Trish and 3 others like this.
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