Effect of Dietary Coenzyme Q10 Plus NADH Supplementation on Fatigue Perception and Health-Related QoL in ... ME/CFS, 2021, Castro-Marrero et al.

[Hutan]

From the Clinical Trials register - the supplement is branded, and there was an objective outcome (HRV) which was not mentioned in the study, and the promised autonomic function results were also not reported.

The secondary outcomes are to examine the effect of oral Reconnect® administration on fatigue perception (assessed by FIS-40), sleep disruption (PSQI), autonomic function (COMPASS-31), Heart Rate Variability (HRV) for measuring R-R intervals by mobile device coupled to the Polar H7 thoracic belt and HRQoL (36-items Short Form Health survey).

It looks as though this team has another trial underway, also aiming to provide a 'scientifically proven!' stamp for another commercial supplement:

Clinical Trial to Assess the Improvement of Fatigue, Sleep Problems, Anxiety / Depression, Neurovegetatives Alterations and Quality of Life After the Administration of ImmunoVita® in Chronic Fatigue Syndrome Patients​

 

[rvallee]

From the Clinical Trials register - the supplement is branded, and there was an objective outcome (HRV) which was not mentioned in the study, and the promised autonomic function results were also not reported.


It looks as though this team has another trial underway, also aiming to provide a 'scientifically proven!' stamp for another commercial supplement:

Clinical Trial to Assess the Improvement of Fatigue, Sleep Problems, Anxiety / Depression, Neurovegetatives Alterations and Quality of Life After the Administration of ImmunoVita® in Chronic Fatigue Syndrome Patients​

ImmunoVita is a food supplement with purified yeast betaglucans (Saccharomyces cerevisiae), vitamin D3, vitamin B6 and zinc.

Hmmm. (X) Doubt.