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Design and validation of a predictive model for determining the risk of developing fibromyalgia 2023 Benachi Sandoval et al

Discussion in ''Conditions related to ME/CFS' news and research' started by Andy, Jan 10, 2023.

  1. Andy

    Andy Committee Member

    Hampshire, UK

    Fibromyalgia is a prevalent disease of unknown aetiology and is difficult to diagnose. Despite the availability of the American College of Rheumatology criteria for diagnosis, it continues to be a challenge in the field of primary health care in terms of identifying individuals with susceptibility to developing the disease. The aim of this study is to design and validate a predictive model of fibromyalgia in subjects with a history of chronic pain.

    This multicentre observational retrospective cohort study was performed on patients aged >18 years, who visited four primary health centres between 2017 and 2020, with a diagnosis of fibromyalgia or arthritis. The Bootstrapping resampling method was used for the validation of the model.

    A total of 198 subjects with fibromyalgia (93 with osteoarthritis, 20 with other types of arthritis, 4 with rheumatoid arthritis) and 120 without fibromyalgia (116 with osteoarthritis, 23 with other types of arthritis, 7 with rheumatoid arthritis) participated in the study. The predictive factors of the final model were self-reported age at onset of symptoms, first-line family history of neurological diseases, exposure to levels of stress, history of post-traumatic acute emotional stress, and personal history of chronic widespread pain prior to diagnosis, comorbidity, and pharmacological prescription during the year of diagnostic confirmation. The predictive capacity adjusted by Bootstrapping was 0.972 (95% CI: 0.955–0.986).

    The proposed model showed an excellent predictive capacity. The risk calculator designed from the predictive model allows health professionals to have a useful tool to identify subjects at risk of developing fibromyalgia.

    Open access, https://www.clinexprheumatol.org/abstract.asp?a=18899
    RedFox and Peter Trewhitt like this.
  2. NelliePledge

    NelliePledge Moderator Staff Member

    UK West Midlands
    History of chronic widespread pain prior to diagnosis in people who then get diagnosed with fibromyalgia well knock me down with a feather :whistle:
  3. Shadrach Loom

    Shadrach Loom Senior Member (Voting Rights)

    London, UK
    It’s certainly a safe bet when the objective is to demonstrate the efficacy of a favoured predictive model . . .
  4. rvallee

    rvallee Senior Member (Voting Rights)

    TL;DR: risk factor for fibromyalgia includes, a history of fibromylagia. So as long as you identify fibromyalgia, you may be able to identify fibromyalgia. Easy peasy.

    Groundbreaking stuff, duderinos. Really sounds like simple clinical work: you listen to the patient's account, apply criteria, and... that's it you're done for now. Imagine that.
    alktipping and Peter Trewhitt like this.

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