COVID-Specific Long-Term Sequelae in Comparison to Common Viral Respiratory Infections: An Analysis of 17,487 Infected Adult Patients 2022,Baskett

Discussion in 'Long Covid research' started by Sly Saint, Jan 5, 2023.

  1. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    ABSTRACT
    Background
    better understanding of long-term health effects after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become one of the healthcare priorities in the current pandemic. We analyzedlarge and diverse patient cohort to study health effects related to SARS-CoV-2 infection occurring more than one month post-infection.

    Methods
    We analyzed 17,487 patients who received diagnoses for SARS-CoV-2 infection in a total of 122 healthcare facilities in the United States prior to April, 14,2022. Patients were propensity score matched with patients diagnosed with the common cold, influenza, or viral pneumonia from March 1, 2020, to April 1, 2021. For each outcome, SARS-CoV-2 was compared to a generic Viral Respiratory Infection (VRI) by predicting diagnoses in the period between 30 and 365 days post-infection. Both COVID-19 and VRI patients were propensity score matched with patients with no record of COVID-19 or VRI and the same methodology was applied. Diagnoses where COVID-19 infection was a significant positive predictor in both COVID-19 vs VRI and COVID-19 vs Control comparisons were considered COVID-19-specific effects.

    Results
    Compared to common VRIs, SARS-CoV-2 was associated with diagnoses palpitations, hair loss, fatigue, chest pain, dyspnea, joint pain, and obesity in the post-infectious period.

    Conclusions
    We identify that some diagnoses commonly described as “long COVID” do not appear significantly more frequent post-COVID-19 infection compared to other common VRIs. We also identify sequelae which are specifically associated with a prior SARS-CoV-2 infection.

    https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofac683/6953331
     
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  2. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    Article about the study

    Not all post COVID-19 condition symptoms are specific to the virus

    https://hospitalpharmacyeurope.com/...condition-symptoms-are-specific-to-the-virus/
     
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  3. RedFox

    RedFox Senior Member (Voting Rights)

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    That's a fairly middling description of ME. They vaguely reference PEM as "exhaustion", describe cognitive impairment as a psychiatric symptom, then describe depression as an ME symptom. (It's not.) I'll cut them slack because PEM-induced mood swings are real, but it's odd of them to emphasize that.
     
  4. ahimsa

    ahimsa Senior Member (Voting Rights)

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    Moved from the Long Covid in the media thread

    Researchers looking for long COVID symptoms find only 7


    https://www.fiercehealthcare.com/providers/researchers-looking-long-covid-symptoms-find-only-seven
    The study being discussed is here: https://academic.oup.com/ofid/article/10/1/ofac683/6953331
     
    Last edited by a moderator: Feb 5, 2023
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  5. rvallee

    rvallee Senior Member (Voting Rights)

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  6. Sean

    Sean Moderator Staff Member

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    Depends on the data. If you are looking at height or number of limbs, for example, it is safe enough.

    But some other data, like psych diagnoses, then not so much.
     
  7. Trish

    Trish Moderator Staff Member

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    The article headline is very misleading. They were looking in the research specifically for symptoms of Long Covid that are different from symptoms of other post viral conditions, not all the symptoms. The 7 they list are, they found, specific to LC, so may be helpful in diagnosing LC.
     

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