Throwing this link in here and hoping it is OK to the idea of the thread - although it seems to apply to measurement of hormones beyond just cortisol, I think it is interesting if the way things should be measured is indeed moving on:
research-information.bris.ac.uk
link to paper: https://academic.oup.com/jes/article/8/4/bvae024/7606556
Just scanned so far but there are interesting points that perhaps relate to other threads such as:
And the interesting part in the discussion before it (which included the issue of sleep affecting measures, but being something you'd want to measure as part of a cycle) reminded me of the dilemma we have with PEM vs exertion, influences impacting things and 'cycles' that we have with ME/CFS and experiments/tests that themselves involve eg travel or even just additional activity even if it was in the home (which then might necessarily cause compensation/change to other activities in a normal week in response)
Clinical Endocrinology—Time for a Reset?
Clinical Endocrinology—Time for a Reset?
Stafford L. Lightman* April 2024Abstract
Measurement of blood levels of circulating hormones has always been the cornerstone of the biochemical diagnosis of endocrine diseases, with the objective of detecting hormone excess or insufficiency. Unfortunately, the dynamic nature of hormone secretion means single-point measurements of many hormones often lack diagnostic validity. Endocrinologists have devised complex dynamic tests as indirect assessments of the functioning of the hormone system under investigation. Recent advances in the measurement of dynamic hormone changes across the day now offer an opportunity to reconsider whether there might be better ways both to diagnose and to monitor the therapy of endocrine conditions.link to paper: https://academic.oup.com/jes/article/8/4/bvae024/7606556
Just scanned so far but there are interesting points that perhaps relate to other threads such as:
- The first lesson is that if we have wearable sensor technology, we should be able to monitor a patient's hormone levels in their own home/work environment—which is, of course, what we actually want to know.
And the interesting part in the discussion before it (which included the issue of sleep affecting measures, but being something you'd want to measure as part of a cycle) reminded me of the dilemma we have with PEM vs exertion, influences impacting things and 'cycles' that we have with ME/CFS and experiments/tests that themselves involve eg travel or even just additional activity even if it was in the home (which then might necessarily cause compensation/change to other activities in a normal week in response)
