Opinion Consequences beyond acute SARS-CoV-2 infection in children, 2024, Saydah et al

forestglip

forestglip

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Consequences beyond acute SARS-CoV-2 infection in children

Sharon H. Saydah, Angela P. Campbell, Adrienne G. Randolph

Abstract
Although most children are spared from developing complications from SARS-CoV-2 infection, some may suffer consequences including Long Covid and multisystem inflammatory syndrome in children (MIS-C). Although the occurrence of these conditions has decreased over time, they can still occur, and recognition of symptoms and prompt diagnosis is imperative for early intervention.

Link | PDF (Science Translational Medicine) [Open Access]
 
Worth mentioning that this, and seven other articles posted today, are from a special issue of Science Translational Medicine dedicated to long COVID (one article is about post-Lyme symptoms).

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The cover image symbolizes the burden that individuals with Long Covid bear as a consequence of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, red virion).

This Special Issue highlights our current knowledge of Long Covid and other infection-associated chronic conditions (IACCs), emphasizing the work required to improve outcomes for the millions of people worldwide affected by IACCs.

An Editorial by Marrazzo et al. describes the goals and impact of the NIH RECOVER Initiative for improving diagnosis and treatment of Long Covid.

Four Viewpoints discuss the long-term effects of COVID-19 in children (Saydah et al.), how Long Covid informs our understanding of other IACCs (Peluso et al.), sex-specific differences in Long Covid (Silva and Iwasaki), and how another IACC, posttreatment Lyme disease, is shedding light on IACC diagnosis and treatment (Marques).

One Review article discusses animal models of Long Covid (Schäfer et al.), and another Review provides a comprehensive analysis of potential drivers of and candidate therapeutics for Long Covid (Antar and Cox).

A Research Article reporting how sex-specific differences during acute COVID-19 correlate with Long Covid development and resolution (Hamlin et al.) completes this Special Issue.
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Link to issue
 
From the article:
Because more severe COVID-19 is associated with persistent symptoms, it is hypothesized that early treatment of COVID-19 with anti–SARS-CoV-2 or anti-inflammatory interventions could potentially decrease the risk of developing Long Covid (Fig. 1B). Vaccination is likely the key to preventing Long Covid in children (13), in part by decreasing the risk of developing a severe acute infection (14, 15).
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That may be useful for people advocating for children to get access to vaccinations. (although I think the protection provided by vaccination is over-stated, as is the protection provided by not being obese).
 
Hutan said:
From the article:

That may be useful for people advocating for children to get access to vaccinations. (although I think the protection provided by vaccination is over-stated, as is the protection provided by not being obese).
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Countries that don't want to vaccinate children use facts such as "70-90% of children have already been infected" as reasons for not providing the vaccine to children in general. There is no need as most have immunity already. While simoultaneously arguing for recent infection not being a reason to not take the vaccine as adults.

No thinking allowed :thumbup:
 
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