Compounded Preparations for Sleep Deprivation

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Compounded Preparations for Sleep Deprivation

March 1, 2024

We are barely three months into the New Year, yet patients may already be complaining of sleep deprivation and exhaustion. With March being National Sleep Month, now is the perfect time to discuss medications to address sleep deprivation. Sleep has a variety of health benefits, including resilience against a number of disease states (like depression) as well as maintaining next-day energy levels. These benefits can in turn help increase weight loss, improve work performance, and decrease social isolation. However, stress from work or even biological processes, such as menopause, may disrupt patients’ sleep schedules. Regardless of the underlying cause, there are a variety of commercially-available and compounded preparations to get patients back on track with a healthy sleep schedule.

Because several drugs call for lower dosages than their commercially-available forms, compounded preparations help tailor the dosage to ensure accurate dosing and maximize a therapy’s effectiveness. Compounding can also be performed to alter the dosage form, which is particularly helpful for patients who have swallowing difficulties, such as older adults. Because any manipulation to a commercially-available medication may drastically alter its release profile or absorption, it’s important that these changes be performed by a licensed compounding pharmacy.

Here are some medications that address sleep deprivation and chronic fatigue.