A high level of lifetime depression and anxiety is also seen in FM and CFS/ME patients, along with those suffering from many other chronic illnesses, but it is not clear to what extent this represents psychological vulnerability or the consequence of living with a chronic debilitating illness (1,4,7). However, it is notable that a large number of sufferers do not meet the criteria for psychological disorders, which suggests that many patients are actually extremely mentally resilient, particularly in the face of the physical suffering inherent in living with one of these conditions (1,7). Furthermore, while patients experiencing major depression may report pain symptoms, they do not necessarily fulfil the criteria necessary for a diagnosis of a pain condition such as FM (4,7).