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Comorbidities in a Nationwide, Heterogenous Population of Veterans with Interstitial Cystitis/Bladder Pain Syndrome, 2021, Laden et al

Discussion in 'Psychosomatic research - ME/CFS and Long Covid' started by Andy, Apr 27, 2021.

  1. Andy

    Andy Committee Member

    Messages:
    16,718
    Location:
    Hampshire, UK
    Abstract

    Objective
    To examine the prevalence of comorbid conditions in a nationwide population of men and women with IC/BPS utilizing a more heterogeneous sample than most studies to date.

    Methods

    Using the Veterans Affairs Informatics and Computing Infrastructure, we identified random samples of male and female patients with and without an ICD-9/ICD-10 diagnosis of IC/BPS. Presence of comorbidities (NUAS [chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, migraines], back pain, diabetes, and smoking) and psychosocial factors (alcohol abuse, post-traumatic stress disorder, sexual trauma, and history of depression) were determined using ICD-9 and ICD-10 codes. Associations between these variables and IC/BPS status were evaluated while adjusting for the potential confounding impact of race/ethnicity, age, and gender.

    Results

    Data was analyzed from 872 IC/BPS patients (355 [41%] men, 517 [59%] women) and 558 non-IC/BPS patients (291 [52%] men, 267 [48%] women). IC/BPS patients were more likely than non-IC/BPS patients to have a greater number of comorbidities (2.72+/-1.77 vs 1.73+/-1.30, p<0.001), experience one or more NUAS (chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, and migraines) (45% [388/872] vs. 18% [101/558]; p<0.001) and had a higher prevalence of at least one psychosocial factor (61% [529/872] v. 46% [256/558]; p<0.001). Differences in the frequencies of comorbidities between patients with and without IC/BPS were more pronounced in female patients.

    Conclusions

    These findings validate the findings of previous comorbidity studies of IC/BPS in a more diverse population.

    Paywall, https://www.goldjournal.net/article/S0090-4295(21)00343-5/fulltext
     
    Trish and Peter Trewhitt like this.
  2. Mithriel

    Mithriel Senior Member (Voting Rights)

    Messages:
    2,632
    Interstitial cystitis is classed as a functional neurological disorder by Stone.
     

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