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Changes in the Allostatic Response to Whole-Body Cryotherapy and Static-Stretching Exercises in CFS Patients vs. Healthy Individuals, 2021, Kujawski

Discussion in 'ME/CFS research' started by Andy, Jul 3, 2021.

  1. Andy

    Andy Committee Member

    Hampshire, UK
    Full title: Changes in the Allostatic Response to Whole-Body Cryotherapy and Static-Stretching Exercises in Chronic Fatigue Syndrome Patients vs. Healthy Individuals.


    This study represents a comparison of the functional interrelation of fatigue and cognitive, cardiovascular and autonomic nervous systems in a group of Chronic Fatigue Syndrome (CFS) patients compared with those in healthy individuals at different stages of analysis: at baseline and after changes induced by whole-body cryotherapy (WBC) combined with a static-stretching (SS) program.

    The study included 32 patients (Fukuda criteria) and 18 healthy controls. Fatigue, cognitive, cardiovascular and autonomic function and arterial stiffness were measured before and after 10 sessions of WBC with SS.

    In the patients, a disturbance in homeostasis was observed. The network relationship based on differences before and after intervention showed comparatively higher stress and eccentricity in the CFS group: 50.9 ± 56.1 vs. 6.35 ± 8.72, p = 0.002, r = 0.28; and 4.8 ± 0.7 vs. 2.4 ± 1, p < 0.001, r = 0.46, respectively. Before and after intervention, in the CFS group increased fatigue was related to baroreceptor function, and baroreceptor function was in turn related to aortic stiffness, but no such relationships were observed in the control group.

    Differences in the network structure underlying the interrelation among the four measured criteria were observed in both groups, before the intervention and after ten sessions of whole cryotherapy with a static stretching exercise.
    Paragraph breaks added.

    Open access, https://www.mdpi.com/2077-0383/10/13/2795/htm
    Michelle, Peter Trewhitt and Trish like this.
  2. Denise

    Denise Senior Member (Voting Rights)

    Fukuda, so this isn't about ME necessarily.
    Enough said for me. (pun intended)
    alktipping and Trish like this.
  3. alktipping

    alktipping Senior Member (Voting Rights)

    sounds awful stretching cold muscles is not a good thing more likely to cause injuries . after all when it comes to exercise we we always told to do warm up stretches .
    Trish likes this.
  4. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

    I don't understand why they only reported the "network relationships", without the results of the individual measures.
    Hutan, Michelle, Amw66 and 3 others like this.
  5. Trish

    Trish Moderator Staff Member

    I agree. There seems to be no mention of whether the treatment made any difference to any of the measures.
    This seems like someone wanted to use a fancy network program which drew pretty diagrams, and forgot there was actually a treatment to be reported on. And they admit they did no correction for multiple comparisons.

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