Causal Relationship Between Diet, Lipids, Immune Cells, and Chronic Fatigue Syndrome: A Two-Mediation Mendelian Randomization Study, 2025, Li et al

[Murph]

I fear that maybe mendelian randomisation studies suck because it is cheap to do. You don't need any samples or pipettes, microscopes or a lab. You need nothing more than a database and a copy of some free stats software. Barriers to entry are low and so, even though the technique can be incredible when done right, in practice it attracts people with no real background in what they are looking at, nor plans to take their study further.

 

[Midnattsol]

hmmm. Affinity for breakfast is a novel concept in medical literature.

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This is the sort of groundbreaking research we need. We should petition to get the name of this illness changed to breakfast affinity syndrome.

[SARCASM TAG INCLUDED HERE FOR FEAR OF MISUNDERSTANDING !!

The wording might be unique, but eating breakfast or not has been a hot topic in nutrition.

Which is also the case with cheese consumption, as saturated fat increase LDL cholesterol and cause cardiovascular events are standard guidance. However studies on dairy can be all over the place (dairy is a common source of saturated fat), and so new hypotheses are made up about dairy being «different». Pork is also seen as different and can be defined as a red meat in some cases and white in others (guidance is typically to avoid red meat) making it impossible to compare studies when only total intakes of specific food groups are reported.

I haven’t read the study, I just wanted to say it should be criticized for the right reasons