Yes it is a shame about the recruitment method. On the plus side, they recruited from two hospital clinics (good) as well as from the local support groups and by social media and posters. I don't agree with you about the patients being more likely to have sore lymph nodes (and, by the way, those with swollen nodes were excluded). Would a pwME who heard about this study really be more likely to volunteer if they have sore lymph nodes? I consulted an osteopath for actual treatment because the Perrin Technique came up quite highly on an MEA survey of treatments. I never gave any thought to my lymph nodes (which for the record are rarely tender and when they are, its my armpits and groin that are sore - I'm not aware of the others until they are pressed). Yes, I'd like to have seen another disease incorporated into this study. To be fair, Perrin hasn't made such a claim.