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Brain fogginess, gas and bloating: a link between SIBO, probiotics and metabolic acidosis, Rao et al, 2018

Discussion in ''Conditions related to ME/CFS' news and research' started by Indigophoton, Jul 10, 2018.

  1. Indigophoton

    Indigophoton Senior Member (Voting Rights)

    TrixieStix, Andy and adambeyoncelowe like this.
  2. MeSci

    MeSci Senior Member (Voting Rights)

    Cornwall, UK
    Interesting. I don't think that antibiotics are necessarily the answer for all of us though, least of all those who are sensitive to medications.

    I note that:

    "We treated all patients with evidence of SIBO with antibiotics and discontinuation of probiotics, and the rest with dietary advice and stopping probiotics. These measures led to significant improvement of symptoms in 70% of our patients and complete resolution of brain fogginess in 85% of patients, reaffirming that the symptoms were related to D-lactic acidosis and SIBO. Likewise, the group of patients without BF, but with either SIBO or D-lactic acidosis also showed similar degree of improvement in symptoms after antibiotics."

    That leaves quite a few who were not helped. I have a feeling that I wouldn't be, having had apparent bad reactions to antibiotics last time I had them (or it may have been to something else).
    adambeyoncelowe and Indigophoton like this.
  3. Ryan31337

    Ryan31337 Senior Member (Voting Rights)

    Really interesting to see L-Lactic acidosis present in some SIBO patients too.

    Could explain why I had a sky-high serum lactate test (L-lactate) one day but not on repeat - only difference that was obvious was one was before a meal and the other was after.
    Pechius, adambeyoncelowe and Trish like this.
  4. DokaGirl

    DokaGirl Senior Member (Voting Rights)

    Interesting article, but I have the opposite effect from antibiotics, and probiotics. Antibiotics greatly increase my brain fog; probiotics reduce it. Antibiotics make me dizzy, often cause GI upset, and Increased BF. Probiotics have always helped BF.

    What triggers your brain fog? For me it's always been antibiotics, carbohydrates, lack of sleep, too much fibre, and sometimes stress will do this too. Things that help are low carb diet, daily probiotics, and heavy metal chelations. I wouldn't say these chelations would be suitable for severe ME due to reactions to chemicals. And, they do pull out good minerals, which have to be replenished.
    andypants likes this.
  5. DokaGirl

    DokaGirl Senior Member (Voting Rights)

    Milk thistle, especially in liquid form has also temporarily helped my BF.
  6. DokaGirl

    DokaGirl Senior Member (Voting Rights)

    The ME micorbiome studies are very interesting for me. Ever since the brain fog started, one of the consistent triggers has been GI pain. Once the GI pain reaches a certain level, I get spaced out, or more spaced out.

    This is how I describe brain fog - a feeling of looking down a tunnel, disoriented, slowed reaction times, confusion, pressure, feeling of squeezing inside my head, can't figure things out. And, this feels different to me than orthostatic intolerance, which makes me feel faint, lightheaded, weak, and uncoordinated.

    Anyone have any other descriptions for brain fog?
    MeSci likes this.
  7. Snowdrop

    Snowdrop Senior Member (Voting Rights)

    I wish someone would test brain fog (I don't really like this term) in the following manner:

    Pick a dozen or so robustly healthy very articulate and intelligent people who run marathons or triathlons and about 1-5 minutes or so after they complete one of these events ask them to complete some simple cognitive tests both oral and written using language and math.

    I don't actually know what the results would look like. But it may be that they have some difficulties doing well. If so, I think this might be what my brain fog looks like.
    MeSci, Hutan and Keela Too like this.
  8. Keela Too

    Keela Too Senior Member (Voting Rights)

    My manual dexterity can decrease- like the way cold fingers won’t work. My speech can go wonky too.
    MeSci, Sisyphus and Hutan like this.
  9. Sisyphus

    Sisyphus Senior Member (Voting Rights)

    Yeah, when I’m in severe brain fog I often get scrawly handwriting at the same time. Not always though, it seems the brain fog comes first, and then as a crash progresses things like handwriting go out.
    MeSci, andypants and Keela Too like this.

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