A couple of years ago a test, done at the University Hospital in Brussels, showed low level Anti nuclear antibody positive with a speckled pattern (1:80). When i asked my UK GP to repeat the test it came back negative. I thought nothing more of it as the result was a low titre. At the end of 2016 the test was repeated by the Hospital in Brussels and this time the titre has increased to 1:60. This didn't surprise me as i have MCAS as well and this result is common in PWMCAS. I recently told my UK GP and she re did the test here, and yet again it came back negative. Can anyone explain why this would be? Its not as if it was a dodgy lab in Brussels. Now The NHS wont accept i have any level of autoimmunity, which if i do might help me to access care of some kind. My GP now wont re refer me to the rheumy. Can anyone explain why this might be? I also have chronically elevated IGM - but only elevated by a small amount.