Article: Three papers help to crack the code of coenzyme Q biosynthesis

https://scienmag.com/three-papers-help-to-crack-the-code-of-coenzyme-q-biosynthesis/

 

Interesting, i have tried to look into this without success in the past (when i had some brain power) so now i know it wasn't my inability to concentrate that was keeping me from finding the info, it has not been discovered yet.
Also it may help us indirectly because if we know how its produced we may be able to back track and learn something about ME/CFS.

 

I'm not sure how, the addition of CoQ10, whilst it provides a few more resources, at least for a while, doesn't prevent PEM, and may hasten it by encouraging inadvisable activities, like thinking.

As such it is, at least for me, in a host of other supplements that appear to give "fake" energy.

How understanding the mechanism would help is currently beyond me.

 

The idea is if we know where it comes form and that its typically reduced in ME/CFS we can try to figure out why and if we come up with some good theories it may help elucidate the disease mechanism of ME/CFS. A long shot but little to lose by trying this angle.
I also found it gave some extra energy, but did not make my PEM worse, but the extra energy seemed to wear off

 

It's typically increasingly reduced in all those over 40, according to my understanding, as all those over 40 don't have ME......

So whilst, if I remember, I will continue to use it as needed, if I need more brain in a week or two's time, I think it's unlikely to be a causal factor.