inox
Senior Member (Voting Rights)
I'm not a fruit fly
but find this article interessting, and wonder if there is a human version.
When I was at my worst, I had hypersomnia, hardly "awake" at all. For me, whatever my ME is, clearly affects my sleep-wake cycles.
https://www.theatlantic.com/science...CBvqtoG6yZX0c8ZTvhgGqPv9f3D4FIKrn5bZ1rfdrSo1U

but find this article interessting, and wonder if there is a human version.
When I was at my worst, I had hypersomnia, hardly "awake" at all. For me, whatever my ME is, clearly affects my sleep-wake cycles.
The sources of these sleep-inducing chemicals have proved surprisingly elusive, and scientists have found only a few that fit the bill. Now Hirofumi Toda from the University of Pennsylvania has discovered another—a gene called nemuri that triggers sleep, at least in fruit flies. Unexpectedly, it alsobecomes active during infections and acts to kill incoming microbes. It seems to be part of a self-regulating system, analogous enough to an internal thermostat that we might call it a sleep-o-stat. It can send animals to sleep when they most need shut-eye, whether because they’re sick or because they just haven’t slept enough.
This ability is intertwined with nemuri’s effects on sleep. Like us, flies sleep more when they get infections. The team found that these bouts of sickness-induced bed rest were longer when they deliberately switched nemuri on, and shorter if they disabled the gene. “There is an intimate link between sleep and the immune system,” Sehgal says.
https://www.theatlantic.com/science...CBvqtoG6yZX0c8ZTvhgGqPv9f3D4FIKrn5bZ1rfdrSo1U