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Alpha lipoic acid

Discussion in 'Drug and supplement treatments' started by Chestnut tree, Sep 11, 2021.

  1. Chestnut tree

    Chestnut tree Established Member (Voting Rights)

    Messages:
    92
    I have been taking ALA (alpha lipoic acid) to stabilize blood sugar dips and it helps really well.

    However I have started to get stomach issues, with headaches, stiff neck and I suspect the ALA.

    I have now stopped the ALA and stomach feels better, however feel very limp because of not taking it.

    Does anyone have any suggestions?
     
  2. alex3619

    alex3619 Senior Member (Voting Rights)

    Messages:
    2,143
    When I have issues with supplements I have various methods I can try though not always with success. The first is to titrate the dose, adjust the dose so that it helps but does not cause problems. The second is to go on and off the supp, not staying on it for long. The third is intense pulse dosing. With resveratrol and now CoQ10 I get best results by taking a dose much higher than recommended on the bottle, but less than is used clinically, titrated to get a result, then go off it for several days. I take my week's dose of both in two doses several days apart, not every day. This works MUCH better for me.

    Another possibility is cofactors. I think B1 is involved, glutathione will be impacted, and there are probably a few others including minerals (magnesium?) , I would have to go back to the literature to refresh my memory. Changes in these might also induce symptoms.
     
  3. MeSci

    MeSci Senior Member (Voting Rights)

    Messages:
    4,499
    Location:
    Cornwall, UK
    I was taking a supplement containing Alpha Lipoic Acid (ALA) and acetyl-L-carnitine for (many?) years, but stopped a few years ago due to possible adverse effects.

    I learned from Phoenix Rising (not always reliable) that ALA should not be taken if one has mercury/amalgam fillings, or within 3 months of getting rid of them: Potential risks of thiol supps: IV glutathione, alpha lipoic acid (ALA), N-acetyl cysteine (NAC) etc | Page 4 | Phoenix Rising ME/CFS Forums

    I have lost all or most of my fillings now, and am trying it occasionally again.
     
  4. Chestnut tree

    Chestnut tree Established Member (Voting Rights)

    Messages:
    92
    Thank you! Cofactors is something I have not looked into.
     
  5. Chestnut tree

    Chestnut tree Established Member (Voting Rights)

    Messages:
    92
    Thank you for the link . Not sure if I have mercury fillings still
     
    MeSci likes this.
  6. Wilhelmina Jenkins

    Wilhelmina Jenkins Senior Member (Voting Rights)

    Messages:
    220
    Location:
    Atlanta, GA, USA
    Is there and published research on the ALA-mercury fillings connection? Does anyone know what the negative effects are supposed to be? (I do take ALA, but I wouldn’t swear that I have any effects from it one way or the other.)
     
  7. MeSci

    MeSci Senior Member (Voting Rights)

    Messages:
    4,499
    Location:
    Cornwall, UK
  8. perchance dreamer

    perchance dreamer Senior Member (Voting Rights)

    Messages:
    1,023
    ALA really disturbed my sleep.
     
    Chestnut tree likes this.
  9. Chestnut tree

    Chestnut tree Established Member (Voting Rights)

    Messages:
    92
    Oh interference with sleep, is bad. Hope it does not bother you now. I take it in the morning. I do not sleep well anyhow haha.
     

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