I'm currently taking nitrofurantoin for an infection. Initially I was so happy to be diagnosed with the infection because I had no idea I had one (only got diagnosed because I passed out at a bus stop, knocked my head and had to go to A&E for concussion...) I thought that getting the infection treated would make me feel a bit better! Sadly I feel worse, totally wiped out I'm trying to find out whether a bad reaction to antibiotics is a symptom of ME/CFS, it seems to be the case for some people? However I can't say for sure whether it is the antibiotics making me feel worse as my symptoms are variable anyway! I definitely do not feel better for taking them - though again it could be the case that the infection is too mild relative to my ME symptoms to make a big impact? I don't know?! Any knowledge on ME + antibiotics here?