A transdiagnostic and biopsychosocial-informed perspective across functional seizures and functional movement disorder, Saxena and Perez, 2021

[Andy]

I can't access the paper, but my money would be on ME being something they consider a FMD.

Huepe-Artigas and colleagues offer important observations on similarities and differences between patients with functional motor disorders (FMD) and those with functional [psychogenic nonepileptic/dissociative] seizures (FS) [1]. Among several findings, the authors identified that the location of bodily related medical events differed between FMD vs. FS (limb predominant for FMD); patients with FS also endorsed more suicidal ideation (56% vs. 32%) and dissociation (31% vs. 4%), while those with FMD frequently had other functional somatic syndromes (46% vs. 27%). Several clinical similarities were also observed, including no between-group differences in terms of psychiatric comorbidities, adverse life experiences, and frequency of medical events preceding symptom onset. The authors concluded that “the pathophysiology may differ between PNES and FMD” and that “larger, perhaps multi-center, studies will be needed to confirm these findings”.

Paywall, https://www.epilepsybehavior.com/article/S1525-5050(20)30929-X/fulltext

 

[alktipping]

Huepe-Artigas and colleagues offer( important )observations on similarities and differences between patients with functional motor disorders (FMD obvious typo it should read as unimportant .

 

[Mithriel]

This is one of those papers that typifies how some research is only needed because of issues which only exist as a result of serious flaws in the basic premise.

One of the core tenets of FND is that it is a single disease caused by emotional problems disturbing brain function which changes because of brain plasticity.

The different presentations of disease, interstitial cystitis, IBS, seizures, dystonia and so on are because the brain has met them before so uses these old pathways or because they served as an emotional crutch or something. It is difficult to work out exactly what they are trying to say beyond the fact it happens.

Since all these things are one disease there should be no difference between the pathology of seizures or movement disorders.

“the pathophysiology may differ between PNES and FMD”

is a blow to the theory.