traumatic brain injury

  1. Andy

    Traumatic brain injury as a chronic disease: insights from the United States Traumatic Brain Injury Model Systems Research Program 2023 Dams-O'Connor

    Traumatic brain injury (TBI) is a global health priority, associated with substantial burden. Historically conceptualised as an injury event with finite recovery, TBI is now recognised as a chronic condition that can affect multiple domains of health and function, some of which might deteriorate...
  2. Andy

    Single and repeated high-level blast, low-level blast, and new-onset self-reported health conditions in the U.S. Millennium Cohort Study: 2023 Belding

    Introduction: Although previous research suggests that overpressure exposure from either high-level blast (HLB) or low-level blast (LLB) are harmful to health, to date no large-scale studies with representative samples of military personnel have utilized prospective designs and self-reported...
  3. L

    Neuropsychological assessment detects patterns of dysfunction associated with brain injury

    Sylvester, R. et al. (2021) The Queen Square Brain Injury Clinic, ACNR. https://acnr.co.uk/articles/the-queen-square-brain-injury-clinic/ Abstract There is recognition of the need for rehabilitation after TBI, but less for expert diagnosis at the level of pathology and impairment during...
  4. Andy

    Extracellular Mitochondria Activate Microglia and Contribute to Neuroinflammation in Traumatic Brain Injury, 2022, Zhang et al

    Abstract Traumatic brain injury (TBI)-induced neuroinflammation is closely associated with poor outcomes and high mortality in affected patients, with unmet needs for effective clinical interventions. A series of causal and disseminating factors have been identified to cause TBI-induced...
  5. L

    Management of traumatic brain injury (TBI): a clinical neuroscience-led pathway for the NHS, 2021, Li et al

    Management of traumatic brain injury (TBI): a clinical neuroscience-led pathway for the NHS Lucia M Li, NIHR clinical lecturer,A Michael D Dilley, consultant neuropsychiatrist,B Alan Carson, consultant neuropsychiatrist and honorary professor,C Jaq Twelftree, AHP consultant in...
  6. Andy

    Vestibulo-ocular dysfunction in mTBI: Utility of the VOMS for evaluation and management. A review, 2022, Kaae et al

    Abstract BACKGROUND: Individuals who have suffered a concussion/mild traumatic brain injury (mTBI) frequently report symptoms associated with vestibular and/or oculomotor dysfunction (VOD) like dizziness, nausea, fatigue, brain fog, headache, gait and neurocognitive impairments which are...
  7. L

    Traumatic brain injury - similarities with and differences to ME/CFS, including PEM

    Thread split from UK NICE 2021 ME/CFS Guideline, published 29th October - post-publication discussion For those who want to share personal experiences on this topic less publicly there is a thread in the members only area here. ______________ I used to think it was unique. But I am starting...
  8. Andy

    UK: The Guardian: "British army veterans denied treatment for brain injuries"

    "They have seizures and brain damage but the MoD insists their illnesses are psychological. Now scans could help thousands of soldiers who have been misdiagnosed" .... "For years, the NHS and the Ministry of Defence have insisted this and other blasts to which Edwards was exposed in a long...
  9. Andy

    Chronic cerebral aspects of long COVID, post-stroke syndromes and similar states share ... perispinal etanercept treatment logic, 2022, Clark

    Full title: Chronic cerebral aspects of long COVID, post-stroke syndromes and similar states share their pathogenesis and perispinal etanercept treatment logic Abstract The chronic neurological aspects of traumatic brain injury, post-stroke syndromes, long COVID-19, persistent Lyme disease, and...
  10. Wyva

    Brain–Immune Interactions as the Basis of Gulf War Illness: Clinical Assessment and Deployment Profile of (...), 2021, Steele, Klimas et al

    Abstract The Boston University-based Gulf War Illness Consortium (GWIC) is a multidisciplinary initiative developed to provide detailed understanding of brain and immune alterations that underlie Gulf War illness (GWI), the persistent multisymptom disorder associated with military service in...
  11. Andy

    UK: NICE Guideline: Rehabilitation for Chronic Neurological Disorders Including Traumatic Brain Injury

    An email from NICE has highlighted that they are developing a guideline on Rehabilitation for Chronic Neurological Disorders Including Traumatic Brain Injury. In theory, NICE, rightly or wrongly, recognise ME as a neurological condition, so I would assume that ME will be included in this...
  12. Andy

    History of Functional Somatic Syndromes and Persistent Symptoms After Mild Traumatic Brain Injury, 2020, Silverberg et al

    Paywall, https://neuro.psychiatryonline.org/doi/10.1176/appi.neuropsych.20060159 Sci hub, no access.
  13. M

    NIH study shows markers in blood can help identify risk for complications after mild Traumatic Brain Injury (TBI)

    Link to article here ... more at the link
  14. Andy

    Microglia and macrophage metabolism in CNS injury and disease: The role of immunometabolism in neurodegeneration and neurotrauma, 2020, Gensel et al

    Open access, https://www.sciencedirect.com/science/article/pii/S0014488620301412
  15. Andy

    Alternative substrate metabolism depends on cerebral metabolic state following traumatic brain injury, 2020, Greco et al

    In rats. Open access, https://www.sciencedirect.com/science/article/pii/S0014488620301205
  16. M

    Traumatic brain injury impairs hormone production, disrupting sleep, cognition, and memory

    This is an article of a paper that is yet to be published. View here. There is much more to the article, discusses a trial with growth hormone. BIAFAC stands for brain injury associated fatigue and altered cognition. It makes me wonder, how many of us had a genuine concussion prior to...
  17. Mij

    Tachycardia in a patient with mild traumatic brain injury, 2019, Jang et al

    Case Report: In conclusion, we describe a patient who showed tachycardia following mild TBI(traumatic brain injury). To our knowledge, this patient is the first reported case of tachycardia following mild TBI. Further studies involving a larger number of subjects showing signs of sympathetic...
  18. J

    Implant improves fatigue and cognition in traumatic brain injury test case, 2019.

    FYI https://www.nytimes.com/2019/04/13/health/implant-brain-injury.html?action=click&module=Discovery&pgtype=Homepage Wonder what the cost is.... Surgery done at Stanford
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