tnf

  1. Sly Saint

    Development and validation of blood-based diagnostic biomarkers for [ME/CFS] using EpiSwitch®… 2025, Hunter et al. (Oxford Biodynamics)

    See here for the abstract and links to the 2025 ME/CFS paper: link See here for a link to a 2024 paper on covid-19 outcomes: link (Development and evaluation of blood-based prognostic biomarkers for COVID disease outcomes using EpiSwitch 3-dimensional genomic regulatory immune-genetic...
    • Sly Saint
    • Thread
    • epigenetics episwitch il-10 il-2 jak-stat machine learning rituximab tnf
    • Replies: 95
    • Forum: ME/CFS research
  2. SNT Gatchaman

    Systemic increase of AMPA receptors associated with cognitive impairment of long COVID, 2025, Fujimoto et al.

    Systemic increase of AMPA receptors associated with cognitive impairment of long COVID Long COVID primarily presents with persistent cognitive impairment (Cog-LC), imposing a substantial and lasting global burden. Even after the pandemic, there remains a critical global need for diagnostic and...
    • SNT Gatchaman
    • Thread
    • ampa astrocytes ccl2 cognitive dysfunction fycompa glutamate japan mri neurons perampanel pet scan synapse tnf
    • Replies: 26
    • Forum: Long Covid research
  3. hotblack

    Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study, 2025, Chen et al

    Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing...
  4. SNT Gatchaman

    Interferon-Linked Lipid and Bile Acid Imbalance Uncovered in Ankylosing Spondylitis in a Sibling-Controlled Multi-Omics Study, 2025, Wang et al.

    Interferon-Linked Lipid and Bile Acid Imbalance Uncovered in Ankylosing Spondylitis in a Sibling-Controlled Multi-Omics Study Ankylosing spondylitis (AS) displays wide inter-patient variability that is not accounted for by HLA-B27 alone, suggesting that additional immune and metabolic...
    • SNT Gatchaman
    • Thread
    • ankylosing spondylitis bile acid fatty acid metabolism fatty acid oxidation il-17 il-23 innate immune system interferon lipids mitochondria neutrophils peroxisome s100 tnf
    • Replies: 5
    • Forum: Other health news and research
  5. forestglip

    A first study of cytokine genomic polymorphisms in CFS: Positive association of TNF-857 and IFNgamma 874 rare alleles, 2006, Carlo-Stella et al

    A first study of cytokine genomic polymorphisms in CFS: Positive association of TNF-857 and IFNgamma 874 rare alleles N Carlo-Stella, C Badulli, A De Silvestri, L Bazzichi, M Martinetti, L Lorusso, S Bombardieri, L Salvaneschi, M Cuccia Published: 2006 [Line breaks added] Objective In the...
  6. SNT Gatchaman

    Endoplasmic Reticulum Stress Amplifies Cytokine Responses in Astrocytes via a PERK/eIF2α/JAK1 Signaling Axis, 2025, Lahiri et al.

    Endoplasmic Reticulum Stress Amplifies Cytokine Responses in Astrocytes via a PERK/eIF2α/JAK1 Signaling Axis Aberrant activation of multiple cellular processes and signaling pathways is a hallmark of many neurological disorders. Understanding how these processes interact is crucial for...
  7. jnmaciuch

    TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis, 2018, Conrad et al.

    TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis Although anti-tumor necrosis factor (TNF) agents are highly effective in the treatment of psoriasis, 2–5% of treated patients develop psoriasis-like skin lesions called paradoxical...
  8. SNT Gatchaman

    Longitudinal lipoprotein and inflammatory mediators analysis uncover persisting inflammation and hyperlipidemia…, 2025, Bae+

    Longitudinal lipoprotein and inflammatory mediators analysis uncover persisting inflammation and hyperlipidemia following SARS-CoV-2 infection in long COVID-19 Bae, Gyuntae; Yang, Zhiqi; Bucci, Daniele; Wegner, Claire; Schäfer, Hartmut; Singh, Yogesh; Lonati, Caterina; Trautwein, Christoph...
  9. SNT Gatchaman

    Effects of a mild inflammatory challenge on cytokines and sickness behavior: A randomized controlled trial using the influenza vaccine, 2025, Jolink+

    Effects of a mild inflammatory challenge on cytokines and sickness behavior: A randomized controlled trial using the influenza vaccine Jolink; Feldman; Antenucci; Cardenas; West; Nakamura; Muscatell The influenza vaccine has reliably been associated with mild, within-person increases in...
  10. SNT Gatchaman

    Proteomics Reveals That Vitamin D Deficiency Leads to Immunoglobulin Abnormalities and Immune Dysregulation in Patients with [LC], 2025, Ji+

    Proteomics Reveals That Vitamin D Deficiency Leads to Immunoglobulin Abnormalities and Immune Dysregulation in Patients with Post-COVID-19 Condition Wenrui Ji; Xiaomin Xie; Guirong Bai; Yalei Fan; Yanting He; Li Zhang; Haiyan Zhou; Ling Li; Huan Li Vitamin D (VD) levels are closely related to...
  11. Mij

    Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk,2025,Van der Stede et al

    Highlights Mononuclear cells are primary drivers of the exercise response in skeletal muscle • Release of histamine from skeletal muscle during exercise from mast cells • Histamine receptor antagonists impair post-exercise muscle glycogen resynthesis • Exercise-induced transcriptional...
    • Mij
    • Thread
    • bdnf biopsy exercise glucose histamine il-6 insulin jak-stat mapk mast cells p53 tgf-β tnf
    • Replies: 6
    • Forum: Other health news and research
  12. SNT Gatchaman

    Identification of an immunological signature of long COVID syndrome, 2025, Guerrera et al.

    Identification of an immunological signature of long COVID syndrome Guerrera, Gisella; Sambucci, Manolo; Timperi, Eleonora; Picozza, Mario; Misiti, Andrea; Placido, Roberta; Corbisiero, Silvia; D’Orso, Silvia; Termine, Andrea; Fabrizio, Carlo; Gargano, Francesca; Eleuteri, Sharon; Marchioni...
  13. Dolphin

    Preprint Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In [ME/CFS],2025, Lee, Cliff et al

    https://www.medrxiv.org/content/10.1101/2025.01.02.24319359v1 Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Ji-Sook Lee1,3, Eliana Lacerda2, Caroline Kingdon 2, Giada Susannini1, Hazel M Dockrell1...
    • Dolphin
    • Thread
    • cliff flow cytometry ifny il-17 kingdon lacerda luis nacul mait cells temra tnf
    • Replies: 45
    • Forum: ME/CFS research
  14. SNT Gatchaman

    Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells, 2024, Gultom et al.

    Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells Gultom, Mitra; Lin, Lin; Brandt, Camilla Blunk; Milusev, Anastasia; Despont, Alain; Shaw, Jane; Döring, Yvonne; Luo, Yonglun; Rieben, Robert Severe acute respiratory syndrome coronavirus 2...
    • SNT Gatchaman
    • Thread
    • coagulation complement endothelial cells endothelial dysfunction spike protein tnf vascular
    • Replies: 0
    • Forum: Long Covid research
  15. SNT Gatchaman

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae, 2024, Narasimhan et al.

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae Narasimhan, Harish; Cheon, In Su; Qian, Wei; Hu, Sheng’en Shawn; Parimon, Tanyalak; Li, Chaofan; Goplen, Nick; Wu, Yue; Wei, Xiaoqin; Son, Young Min; Fink, Elizabeth; de Almeida Santos, Gislane; Tang, Jinyi; Yao, Changfu...
  16. SNT Gatchaman

    Immune system adaptation during gender-affirming testosterone treatment, 2024, Lakshmikanth, Brodin et al.

    Immune system adaptation during gender-affirming testosterone treatment Lakshmikanth, Tadepally; Consiglio, Camila; Sardh, Fabian; Forlin, Rikard; Wang, Jun; Tan, Ziyang; Barcenilla, Hugo; Rodriguez, Lucie; Sugrue, Jamie; Noori, Peri; Ivanchenko, Margarita; Piñero Páez, Laura; Gonzalez, Laura...
  17. SNT Gatchaman

    Cytokine Profile in Patients with Postacute Sequelae of COVID-19, 2024, Ghorra et al.

    Cytokine Profile in Patients with Postacute Sequelae of COVID-19 Nathalie Ghorra; Alexandros Popotas; Tatiana Besse-Hammer; Anne Rogiers; Francis Corazza; Carole Nagant The enduring impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease manifestation, COVID-19...
  18. Dolphin

    Preprint Impact of inflammatory response in the acute phase of COVID-19 on predicting objective and subjective post-COVID fatigue, 2024, Péron

    https://www.researchsquare.com/article/rs-4374986/v1 Article Impact of inflammatory response in the acute phase of COVID-19 on predicting objective and subjective post-COVID fatigue Julie Péron Anthony Nuber-Champier Gautier Breville Philippe Voruz Isabele Jacot de Alcântara Patrice Lalive...
  19. SNT Gatchaman

    Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α, 2024, Queiroz et al.

    Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α Queiroz, Maria Alice Freitas; Brito, Wandrey Roberto dos Santos; Pereira, Keise Adrielle Santos; Pereira, Leonn Mendes Soares; Amoras, Ednelza da Silva Graça; Lima, Sandra Souza; Santos, Erika Ferreira...
  20. SNT Gatchaman

    Cytokines IL1β, IL6, TNFα & serum cortisol may not constitute reliable biomarkers to identify [PASC], 2024, Fleischer, Kleinschnitz et al.

    Cytokines IL1β, IL6, TNFα and serum cortisol levels may not constitute reliable biomarkers to identify individuals with post-acute sequelae of COVID-19 Michael Fleischer; Fabian Szepanowski; Anne K Mausberg; Livia Asan; Ellen Uslar; Denise Zwanziger; Lothar Volbracht; Mark Stettner; Christoph...
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