subjective outcomes

Abstract Background In this qualitative study, we aimed to obtain and synthesise the views of patients with functional neurological disorder (FND), their caregivers, and relevant healthcare professionals (HCPs) on outcome measurement in FND. Methods Semi-structured interviews were conducted...

Full title: Comparative effectiveness of cognitive behavioural therapy, modafinil, and their combination for treating fatigue in multiple sclerosis (COMBO-MS): a randomised, statistician-blinded, parallel-arm trial Background Fatigue is one of the most disabling symptoms reported by people...

Assessing severity of illness and outcomes of treatment in children with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME): a systematic review of patient-reported outcome measures (PROMs) K L Haywood 1, S M Collin, E Crawley Abstract Chronic Fatigue Syndrome or Myalgic...

https://www.sheffield.ac.uk/scharr/research/centres/ctru/mss3 I don't see a thread on this. The list of contributors imply a very expensive price tag for doing copy-paste research that's been done many times before. No idea if ME is an exclusion criteria, very few details. Obviously not a...

Abstract Background: Patient-reported outcome measures (PROMs) are often used in clinical research, but little is known about their performance as longitudinal outcomes. Methods: We used data from ASCEND, a large SPMS trial (n = 889), to investigate changes on the Short Form Health Survey 36...

First trans-diagnostic experiences with a novel micro-choice based concentrated group rehabilitation for patients with low back pain, long COVID, and type 2 diabetes: a pilot study Kvale, Gerd; Søfteland, Eirik; Jürgensen, Marte; Wilhelmsen-Langeland, Ane; Haugstvedt, Anne; Hystad, Sigurd...

Treatment of 95 post-Covid patients with SSRIs Rus, Carla P.; de Vries, Bert E. K.; de Vries, Ingmar E. J.; Nutma, Idelette; Kooij, J. J. Sandra After Covid-19 infection, 12.5% develops post-Covid-syndrome (PCS). Symptoms indicate numerous affected organ systems. After a year, chronic fatigue...

Critical Appraisal Tools, University of Oxford So while looking for something else I came across this website with "critical appraisal tools" for various study types: https://www.cebm.ox.ac.uk/resources/ebm-tools/critical-appraisal-tools On randomised controlled trials it is said on blinding...

Bias was reduced in an open-label trial through the removal of subjective elements from the outcome definition Objective: To determine whether modifying an outcome definition to remove subjective elements reduced bias in a trial that could not use blinded outcome assessment. Study design and...

Anker, S D, Agewall, S, Borggrefe M et al, 2014, The importance of patient-reported outcomes: a call for their comprehensive integration in cardiovascular clinical trials, European Heart Journal, Volume 35, Issue 30, 7 August 2014, Pages 2001–2009, https://doi.org/10.1093/eurheartj/ehu205...

https://theconversation.com/flawed-data-led-to-findings-of-a-connection-between-time-spent-on-devices-and-mental-health-problems-new-research-162585 Craig Sewall is a Postdoctoral Scholar of Child and Adolescent Mental Health at the University of Pittsburgh. He explains that studies on the...

(This is a reference to the discussion on bias due to a lack of blinding here.) Bull, L. (2007). Sunflower therapy for children with specific learning difficulties (dyslexia): A randomised, controlled trial. Complementary Therapies in Clinical Practice, 13(1), 15–24...

Darragh, M., Chang, J. W.-H., Booth, R. J., & Consedine, N. S. (2015). The placebo effect in inflammatory skin reactions. Journal of Psychosomatic Research, 78(5), 489–494. doi:10.1016/j.jpsychores.2015.01.011 ResearchGate link here Scihub link here This study found that a placebo cream...

Full title: An exploratory study of discrepancies between objective and subjective measurement of the physical activity level in female patients with chronic fatigue syndrome Highlights • There is a discrepancy between self-report and objective activity measures in CFS. • The activity diary...

When is lack of scientific integrity a reason for retracting a paper? A case study. Abstract: This editorial has just come out in the Journal of Psychosomatic Research. It is a discussion of issues that arose from this 2004 publication: This study is a triple-blinded randomised controlled...

Vink M, Vink-Niese A. The draft updated NICE guidance for ME/CFS highlights the unreliability of subjective outcome measures in non-blinded trials. Journal of Health Psychology. January 2021 (Editorial), doi:10.1177/1359105321990810...