stress

  1. InitialConditions

    Stress dynamically modulates neuronal autophagy to gate depression onset - Yang et al., 2025

    Chronic stress remodels brain homeostasis, in which persistent change leads to depressive disorders. As a key modulator of brain homeostasis, it remains elusive whether and how brain autophagy is engaged in stress dynamics. Here we discover that acute stress activates, whereas chronic stress...
  2. ElephantNerd

    How to talk about stress without implying psychosomatic illness

    Hi, this is my first discussion thread so mods pls tell me if there is another thread I'm missing that covers this topic. I'm trying to figure out a good way to discuss with family, friends, and medical providers the relationship between stress and ME and POTS/dysautonomia. Obviously ME and...
  3. forestglip

    Why are women more fatigued than men? The roles of stress, sleep, and repetitive negative thinking, 2025, Golmohamadi et al

    Why are women more fatigued than men? The roles of stress, sleep, and repetitive negative thinking Shima Golmohamadi, Bronwyn M. Graham [Line breaks added] Abstract Fatigue, a state of prolonged tiredness that cannot be alleviated through rest, is twice as likely to affect women than men. To...
  4. forestglip

    Chronic stress and post-traumatic stress in long COVID: a comparative survey study, 2025, Oehlke et al

    Chronic stress and post-traumatic stress in long COVID: a comparative survey study Sofia-Marie Oehlke, Annika Lozar, Andreas Goreis, Diana Klinger, Paul L. Plener & Oswald D. Kothgassner Published: 5 March 2025 Abstract Long COVID (LC) is a prevalent condition among SARS-CoV-2 infections...
  5. forestglip

    Prevalence and severity of anxiety, stress, and depression in long COVID among adults in Barcelona, 2025, León-Gómez et al

    Prevalence and severity of anxiety, stress, and depression in long COVID among adults in Barcelona Brenda Biaani León-Gómez, Meritxell Carmona-Cervelló, Rosalia Dacosta-Aguayo, Noemí Lamonja-Vicente, Jofre Bielsa-Pascual, Victor M López-Lifante, Valeria Zamora-Putin, Gemma Molist, Pilar...
  6. Yann04

    The neuroendocrinology of stress and the importance of a proper balance between the mineralocorticoid and glucocorticoid receptors, 2024, Gold & Wong

    (Guest Editorial) No Abstract Provided — First two paragraphs This editorial highlights two elegant articles published recently about the stress response in health and disease: Agorastos and Chrousos [1] and de Kloet and Joels [2]. Chrousos, the senior author of the first paper, is arguably...
  7. SNT Gatchaman

     Early-life stress and the gut microbiome: A comprehensive population-based investigation, 2024, Mulder et al.

     Early-life stress and the gut microbiome: A comprehensive population-based investigation Mulder; Kraaij; Schuurmans; Frances-Cuesta; Sanz; Medina-Gomez; Duijts; Rivadeneira; Tiemeier; Jaddoe; Felix; Cecil Early-life stress (ELS) has been robustly associated with a range of poor mental and...
  8. SNT Gatchaman

    Hypothalamus volumes in adolescent [ME/CFS]: Impact of self-reported fatigue and illness duration, 2023, Byrne et al.

    Hypothalamus volumes in adolescent Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Impact of self-reported fatigue and illness duration Hollie Byrne; Elisha K Josev; Sarah J Knight; Adam Scheinberg; Katherine Rowe; Lionel Lubitz; Marc L Seal Adolescent Myalgic Encephalomyelitis/Chronic...
  9. D

    Impact of Stress Upon Cancer Metastasis, 2010, Moreno-Smith et al

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037818/ Abstract The influence of psychosocial factors on the development and progression of cancer has been a longstanding hypothesis since ancient times. In fact, epidemiological and clinical studies over the past 30 years have provided strong...
  10. Sly Saint

    Article: Everything you know about stress and high blood pressure is wrong

    but https://www.axios.com/2022/12/14/hypertension-stress-high-blood-pressure-mind-body-wellness-pandemic
  11. Sly Saint

    Increases in Stress Hormone Levels in a UK Population During in the COVID-19 Pandemic: A Prospective Cohort Study 2022 Jia,Chalder et al

    Highlights • Hair cortisone significantly increased by 23% in response to the COVID-19 pandemic • Stress at the start of the pandemic associated with greater increases in cortisol • Increased cortisone more likely in people with previous mental health difficulties Abstract Background Research...
  12. Wyva

    Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post–COVID-19 Conditions, 2022, Wang et a

    Key Points Question Is psychological distress before SARS-CoV-2 infection associated with risk of COVID-19–related symptoms lasting 4 weeks or longer, known as post–COVID-19 conditions? Findings This cohort study found that among participants who did not report SARS-CoV-2 infection at...
  13. Wyva

    Preprint: Does pre-infection stress increase the risk of long COVID? Longitudinal associations between adversity worries (...), 2022, Paul, Fancourt

    Full title: Does pre-infection stress increase the risk of long COVID? Longitudinal associations between adversity worries and experiences in the month prior to COVID-19 infection and the development of long COVID and specific long COVID symptoms Abstract Background Long COVID is increasingly...
  14. Sly Saint

    Psychological Predictors of Self-reported COVID-19 Outcomes: Results From a Prospective Cohort Study, 2022, Ayling, Chalder et al

    Abstract Background Previous research has shown that psychological factors, such as stress and social support, are associated with greater susceptibility to viral respiratory illnesses and more severe symptoms. During the COVID-19 pandemic there has been a well-documented deterioration in...
  15. Sly Saint

    The Intricate Web of Fatigue in Women, 2021,Mathis

    Abstract The modern woman has taken her rightful place in society as a worker, a caregiver, a mother, and a world citizen. However, along with the privileges of these roles comes the great cost of stress and resultant exhaustion and fatigue. Psychosocial, physical, cultural, and disease-related...
  16. Anna H

    Self-soothing touch and being hugged reduce cortisol responses to stress... , 2021, Dreisoernera et al

    Self-soothing touch and being hugged reduce cortisol responses to stress: A randomized controlled trial on stress, physical touch, and social identity Aljoscha Dreisoernera,*, Nina M. Junkera, Wolff Schlotza,b, Julia Heimricha, Svenja Bloemekec, Beate Ditzend, Rolf van Dicka Abstract...
  17. Andy

    The impact of COVID-19 stress on pain and fatigue in people with and without a central sensitivity syndrome, 2021, Kopperta et al

    Highlights • Stress may augment somatic symptoms in central sensitivity syndromes (CSS). • The COVID-19 pandemic offers a unique context to examine this hypothesis. • No convincing evidence indicated a COVID-19 stress-somatic symptoms link. • Also, no buffering effect of psychological...
  18. Sly Saint

    Impact of Life Stressors on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Symptoms: An Australian Longitudinal Study, 2021, Balinas,Staines et al

    Abstract (1) Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, multifaceted illness. The pathomechanism, severity and progression of this illness is still being investigated. Stressors have been implicated in symptom exacerbation for ME/CFS, however, there is...
  19. Andy

    Changes in Kynurenine Pathway Metabolites After Acute Psychosocial Stress in Healthy Males: A Single-Arm Pilot Study, 2021, La Torre et al

    Abstract Chronic stress is associated with an increased conversion of tryptophan (TRP) into kynurenine (KYN). However, only a few studies investigated KYN pathway metabolite concentrations following acute stress in healthy subjects. We hypothesized that TRP/KYN metabolism changes following...
  20. Michelle

    Medscape: The Anxious History of Understanding Cortisol

    Medscape: The Anxious History of Understanding Cortisol Came across this on Medscape today and since we've been having discussions on what "stress" is elsewhere on the forum--to say nothing of the many discussions on cortisol and ME/CFS over many years--it seemed a bit interesting to see how...
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