SARS-CoV-2 S1 subunit produces a protracted priming of the neuroinflammatory, physiological, and behavioral responses to a remote immune challenge: A role for corticosteroids
Frank; Ball; Hopkins; Kelley; Kuzma; Thompson; Fleshner; Maier
Long COVID is a major public health consequence of...
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation
Rainer Knoll; Elisa T. Helbig; Kilian Dahm; Olufemi Bolaji; Frederik Hamm; Oliver Dietrich; Martina van Uelft; Sophie Müller; Lorenzo Bonaguro; Jonas Schulte-Schrepping; Lev Petrov...
Mitochondrial quality control pathways sense mitochondrial protein import
Laurie P. Lee-Glover; Timothy E. Shutt
Mitochondrial quality control (MQC) mechanisms are required to maintain a functional proteome, which enables mitochondria to perform a myriad of important cellular functions from...
Early in the summer I had a synthetic corticosteroid injection (Kenalog: Triamcinolone acetonide) for joint pain. To my surprise, I no longer experience the same lymph node pain and flu-like feeling on exertion. As a result I have an increased capacity for activity. It's been several months now...
https://www.theguardian.com/science/2020/oct/25/the-dementia-that-can-be-cured
The dementia that can be cured
Treatments mentioned include steroids, rituximab and plasma exchange.
Full title: General theory of inflammation: patient self-administration of hydrocortisone safely achieves superior control of hydrocortisone-responding disorders by matching dosage with symptom intensity
Open access at...
This is worth a revisit and is something which I have followed since 1999.
I know it's old but we as a family have followed this treatment since 1999 and it's approach and are revisiting it.
We are lucky to have a pragmatic open minded GP who supports the approach...
Just upfront, I’m not looking for medical advice, just any experience of side effects to look out for taking Prednisolone
Had a strange allergic reaction on Saturday...stupidly was just showing my son the electric sander not realising that it was still full of sawdust...well poof and a got a...
I am going off of steroids due to my severe intolerance of being able to take them. Prednisone was like valium to me. I slept constantly and Medrol has made me crazy. I have been agitated, anxious, talking to myself and unable to sleep. At times I feel manic on it at only 2 mg.
Does anyone...
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