sjogrens

  1. jnmaciuch

    Timeline of interferon, autoantibodies, and autoimmune disease development

    Posting several links exploring temporal dynamics between interferon, autoantibodies, and autoimmune diseases (primarily lupus). (Review) Emerging concepts of type I interferons in SLE pathogenesis and therapy Note: SLE = systemic lupus erythematosus Links to references are active in the...
  2. forestglip

    Improved Fatigue Management in Primary Sjögren's Syndrome: A Retrospective Analysis of the Efficacy of Methotrexate in Chinese Patients, 2024, Zhou+

    Improved Fatigue Management in Primary Sjögren's Syndrome: A Retrospective Analysis of the Efficacy of Methotrexate in Chinese Patients Meiju Zhou, Xiaona Dai, Fang Yuan Abstract Objective: To assess the efficacy of methotrexate (MTX) and hydroxychloroquine (HCQ) in improving fatigue...
  3. Joan Crawford

    Epstein–Barr virus as a potentiator of autoimmune diseases

    Epstein–Barr virus as a potentiator of autoimmune diseases William H. Robinson, Shady Younis, …Tobias V. Lanz Show authors Nature Reviews Rheumatology (2024)Cite this article Metricsdetails Abstract The Epstein–Barr virus (EBV) is epidemiologically associated with development of autoimmune...
  4. SNT Gatchaman

    Interferon gene expression declines over time post-COVID infection and in long COVID patients, 2024, Gómez-Carballa et al.

    Interferon gene expression declines over time post-COVID infection and in long COVID patients A. Gómez-Carballa; S. Pischedda; J. Pardo-Seco; J. Gómez-Rial; F. Martinón-Torres; A. Salas BACKGROUND Interferons (IFNs) represent a first-line defense against viruses and other pathogens. It has been...
  5. P

    Exploring the clinical and immunopathological association between Long COVID and Sjögren's Disease in mice and humans

    Exploring the clinical and immunopathological association between Long COVID and Sjögren's Disease in mice and humans Sponsored by: Olink Proteomics +25pts SPEAKER Cuong Nguyen, PhD Associate Professor, University of Florida BIOGRAPHY EVENT DATE & TIME Date: May 30, 2024 Time: 9:00 AM...
  6. M

    Identification of distinct subgroups of Sjögren's disease by cluster analysis based on clinical and biological manifestations... (2024) Nguyen et al.

    Full title: Identification of distinct subgroups of Sjögren's disease by cluster analysis based on clinical and biological manifestations: data from the cross-sectional Paris-Saclay and the prospective ASSESS cohorts Summary Background Sjögren's disease is a heterogenous autoimmune disease...
  7. P

    Autoantibodies identify primary Sjögren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B, Longobardi et al, 2023

    https://pubmed.ncbi.nlm.nih.gov/37147113/ Abstract Objective: Identify autoantibodies in anti-Ro/SS-A negative primary Sjögren's syndrome (SS). Methods: This is a proof-of-concept, case-control study of SS, healthy (HC) and other disease (OD) controls. A discovery dataset of plasma samples...
  8. P

    Metabolic Disorders Causing Fatigue and Exercise intolerance in Sjogren’s Syndrome, 2014 Suresh et al

    Metabolic Disorders Causing Fatigue in Sjogren’s Syndrome ABSTRACT NUMBER: 2546 Metabolic Disorders Causing Fatigue in Sjogren’s Syndrome Lakshmanan Suresh1, Julian Ambrus2, Long Shen3 and Sahana Vishwanath4, 160 Pineview Drive, State University of New York/Buffalo, Buffalo, NY, 2100 High St...
  9. E

    Dazodalibep (VIB4920/HZN4920) in Sjögren’s Subjects with an Unacceptable Symptom Burden: Safety and Efficacy from a Phase 2, Randomized, Double-Blind

    LB0003 Dazodalibep (VIB4920/HZN4920) in Sjögren’s Subjects with an Unacceptable Symptom Burden: Safety and Efficacy from a Phase 2, Randomized, Double-Blind Study Abstract Background Sjögren’s is a systemic autoimmune disease associated with marked morbidity and poor health-related quality of...
  10. Sly Saint

    Sjögren's Saliva Gland Abnormalities Worsen Over Time, Study Shows

    Sjögren's Saliva Gland Abnormalities Worsen Over Time, Study Shows | Mirage News
  11. Sly Saint

    Amgen reports data from Sjögren’s Syndrome treatment trial

    Amgen reports data from Sjögren’s Syndrome treatment trial (clinicaltrialsarena.com)
  12. SNT Gatchaman

    Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19, 2023, Lim et al.

    Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19 Sung Ha Lim; Hyun Jeong Ju; Ju Hee Han; Ji Hae Lee; Won-Soo Lee; Jung Min Bae; Solam Lee Importance Multiple cases of autoimmune and autoinflammatory diseases after COVID-19 have been reported. However, their...
  13. J

    Efficacy of daratumumab in refractory primary Sjögren disease Nocturne 2023

    https://rmdopen.bmj.com/content/9/3/e003464 Here, we report the first two cases of patients with severe complications of SjD, refractory to RTX and successfully treated with daratumumab.
  14. Sly Saint

    Characterizing Sjögren-Associated Fatigue: A Distinct Phenotype from ME/CFS, 2023, Scheibenbogen et al

    Abstract: Fatigue is the most commonly reported and debilitating extraglandular symptom of primary Sjögren′s syndrome (pSS). Fatigue and exertional intolerance are hallmark symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We aimed to characterize fatigue and further...
  15. Sly Saint

    Opinion: Hope on the Horizon for Sjogren’s Syndrome | BioSpace

    full article https://www.biospace.com/article/opinion-hope-on-the-horizon-for-sjogren-s-syndrome/
  16. SNT Gatchaman

    [Preprint] Evidence of a Sjögren’s disease-like phenotype following COVID-19, 2022, Shen et al

    Evidence of a Sjögren’s disease-like phenotype following COVID-19 Objectives Sjögren’s Disease (SjD) is a chronic and systemic autoimmune disease characterized by lymphocytic infiltration and the development of dry eyes and dry mouth resulting from the secretory dysfunction of the exocrine...
  17. Mij

    Risk of primary Sjogren’s Syndrome following human papillomavirus infections: a nationwide population-based cohort study, 2022, Huang-Hsi Chen et al

    Introduction: Viral infection is an exogeneous factor for primary Sjogren’s syndrome (pSS). This study investigated the association between human papillomavirus (HPV) infections and pSS through a nationwide population based cohort study. Methods: Patients with HPV infections between January...
  18. Wyva

    The interplay between cognition, depression, anxiety, and sleep in primary Sjogren’s syndrome patients, 2022, Goulabchand et al

    Abstract Primary Sjögren’s syndrome (pSS) is an autoimmune disease with frequent neurological involvement. Memory complaints are common, but their precise patterns remain unclear. We wanted to characterize patterns of neurocognitive profiles in pSS patients with cognitive complaints. Only pSS...
  19. Andy

    Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren’s syndrome, 2021, Barrera et al

    Highlights • Chronic inflammation can be caused by organelle (e.g., mitochondria) malfunction. • Dysfunctional mitochondria release DAMPs that trigger inflammation through PRRs. • Salivary cells’ mitochondria show ultrastructural alterations in Sjögren’s syndrome. • Endoplasmic reticulum...
  20. Sly Saint

    Delayed-type hypersensitivity to metals in connective tissue diseases and fibromyalgia, 2017, Bjorklund et al

    https://www.sciencedirect.com/science/article/abs/pii/S0013935117317280?via%3Dihub
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