Background Despite earlier doubts, a string of recent successes indicates that if sample sizes are large enough, it is possible—both in theory and in practice—to identify and replicate genetic associations with common complex diseases.
But human genome epidemiology is expensive and, from a...
R Jones, S Carley, M Harrison. An introduction to power and sample size estimation. Emerg Med J2003;20:453–458
The importance of power and sample size estimation for study design and analysis.
OBJECTIVES
1. Understand power and sample size estimation.
2 Understand why power is an important...
The importance of estimating sample sizes is rarely understood by researchers, when planning a study. This paper aims to highlight the centrality of sample size estimations in health research. Examples that help in understanding the basic concepts involved in their calculation are presented...
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