Abstract
The immunoregulatory metabolite itaconate accumulates in innate immune cells upon Toll-like receptor stimulation. In response to macrophage activation by lipopolysaccharide, itaconate inhibits inflammasome activation and boosts type I interferon signalling; however, the molecular...
Good day my peeps,
I would like to know if anyone has tried Red Light Therapy with a proper device (quality, third party tested etc.). If yes, what was your experience? Thank you...
Low-Intensity Light Therapy: Exploring the Role of Redox Mechanisms - PMC
Mitochondria and oxygen homeostasis
Mateus P. Mori; Rozhin Penjweini; Jay R. Knutson; Ping-yuan Wang; Paul M. Hwang
Molecular oxygen possesses a dual nature due to its highly reactive free radical property: it is capable of oxidizing metabolic substrates to generate cellular energy, but can...
Exercise and vascular function in sedentary lifestyles in humans
Fasipe, Babatunde; Li, Shunchang; Laher, Ismail
People with sedentary lifestyles engage in minimal or no physical activity. A sedentary lifestyle promotes dysregulation of cellular redox balance, diminishes mitochondrial function...
Abstract
Oocytes form before birth and remain viable for several decades before fertilization1. Although poor oocyte quality accounts for most female fertility problems, little is known about how oocytes maintain cellular fitness, or why their quality eventually declines with age2. Reactive...
Highlights
• Patients hospitalized for COVID-19 display marked impairment in endothelial function, which is persistent following recovery from the acute infection.
• Red blood cells (RBCs) from patients with COVID-19 impair vascular function through mechanisms involving increased arginase 1...
Abstract
Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, has been shown to accelerate the progression of atherosclerosis (AS). However, the definite mechanisms remain elusive. Emerging evidence supports an association between mitochondrial dysfunction and AS.
In our...
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