post-translational modification

  1. SNT Gatchaman

    Advancing understanding of long COVID pathophysiology through quantum walk-based network analysis, 2026, Park et al.

    Advancing understanding of long COVID pathophysiology through quantum walk-based network analysis MOTIVATION Long COVID is a multisystem condition characterized by persistent symptoms such as fatigue, cognitive impairment, and systemic inflammation following COVID-19 infection. However, its...
    • SNT Gatchaman
    • Thread
    • calcium cdgsh coagulation extracellular matrix mitochondria neuroinflammation post-translational modification thromboinflammation vdac1
    • Replies: 4
    • Forum: Long Covid research
  2. SNT Gatchaman

    Multi-System Genetic Architecture of Hypermobile Ehlers–Danlos Syndrome: Integrating [ML] with Subject-Level Genomic Analysis, 2026, Shirvani+

    Multi-System Genetic Architecture of Hypermobile Ehlers–Danlos Syndrome: Integrating Machine Learning with Subject-Level Genomic Analysis BACKGROUND/OBJECTIVES Hypermobile Ehlers–Danlos syndrome (hEDS) remains genetically unexplained despite decades of clinical investigation, with the...
  3. SNT Gatchaman

    Review Post-Translational Modification & Subcellular Compartmentalization: Emerging Concepts on the Regulation … of RhoGTPases, 2021, Navarro-Lérida+

    Post-Translational Modification and Subcellular Compartmentalization: Emerging Concepts on the Regulation and Physiopathological Relevance of RhoGTPases Navarro-Lérida, Inmaculada; Sánchez-Álvarez, Miguel; del Pozo, Miguel Ángel Cells and tissues are continuously exposed to both chemical and...
    • SNT Gatchaman
    • Thread
    • actin autophagy cholesterol cytoskeleton endoplasmic reticulum extracellular matrix integrins lipid rafts lipids post-translational modification rho gtpase sumo ubiquitination
    • Replies: 3
    • Forum: Other health news and research
  4. SNT Gatchaman

    Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation, 2026, Zuo et al.

    Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation Glycolysis is a central metabolic pathway that converts glucose into pyruvate. Although pyruvate has been well documented to be a key and terminal metabolite of glycolysis with both energetic and...
  5. SNT Gatchaman

    Widespread ncaas Imprints in the Serum Proteome of COVID-19 Convalescents Uncovering Immune System Sequelae, 2026, Liu et al.

    Widespread ncaas Imprints in the Serum Proteome of COVID-19 Convalescents Uncovering Immune System Sequelae Post-COVID-19 sequelae has become an emerging global health issue, but the mechanisms for the sustained susceptibility of convalescents to the sequelae remain poorly understood. Here we...
    • SNT Gatchaman
    • Thread
    • amino acids carboxypeptidase clusterin coagulation complement factor d factor h fibrinolysis ficolin igg3 immunoglobulin lectin post-translational modification proteomics thrombospondin-1
    • Replies: 6
    • Forum: Long Covid research
  6. mariovitali

    Preprint Post-translational modifications within fibrinaloid microclot complexes distinguish [Pre-COVID-19 POTS, LC, and LC-POTS] [...], 2025, Booyens et al

    Post-translational modifications within fibrinaloid microclot complexes distinguish Pre-COVID-19 Postural Orthostatic Tachycardia Syndrome (POTS), Long COVID, and Long COVID-POTS and reveal disease-specific molecular pathways Background: Pre-COVID-19 Postural orthostatic tachycardia syndrome...
    • mariovitali
    • Thread
    • complement fibrin amyloid microclots lipids long covid microclots post-translational modification pots
    • Replies: 1
    • Forum: Long Covid research
  7. SNT Gatchaman

    Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in [LC], 2025, Shahbaz+

    Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients Shahbaz; Rezaeifar; Syed; Redmond; Terveart; Osman; Elahi A substantial portion of patients infected with SARS-CoV-2 experience prolonged complications...
    • SNT Gatchaman
    • Thread
    • artemin kir neutrophils nk cells olfactory olfactory receptors post-translational modification reelin runx2 t cells tgf-beta transcriptomics vegf-b
    • Replies: 3
    • Forum: Long Covid research
  8. Mij

    CCL2-mediated endothelial injury drives cardiac dysfunction in long COVID, 2024, Dilip Thomas et al

    Abstract Evidence linking the endothelium to cardiac injury in long coronavirus disease (COVID) is well documented, but the underlying mechanisms remain unknown. Here we show that cytokines released by endothelial cells (ECs) contribute to long-COVID-associated cardiac dysfunction. Using...
    • Mij
    • Thread
    • acetylcholine calcium cardiac ccl2 cytokines endothelial cells endotheliitis fibronectin glycocalyx il-6 monocytes nf-κb nitric oxide post-translational modification spike protein
    • Replies: 4
    • Forum: Long Covid research
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