peroxiredoxin

  1. Mij

    Redox proteomics reveal a role for peroxiredoxinylation in stress protection, 2025, Gerhard Seisenbacher et al

    Highlights -The peroxiredoxin Tsa1 interacts with a large fraction of the proteome in a redox manner -Covalent Tsa1 attachment to target proteins (peroxiredoxinylation) increases upon stress -Metabolic enzymes and proteins involved in translation are targeted by Tsa1 -Stress survival requires...
  2. Mij

    Itaconate modulates immune responses via inhibition of peroxiredoxin 5, 2025, Tomas Paulenda et al

    Abstract The immunoregulatory metabolite itaconate accumulates in innate immune cells upon Toll-like receptor stimulation. In response to macrophage activation by lipopolysaccharide, itaconate inhibits inflammasome activation and boosts type I interferon signalling; however, the molecular...
  3. Mij

    Itaconate boosts type I IFN response by disrupting cytoprotection, 2025, Theresa Ramalho

    A new study reveals a surprising mechanism by which itaconate inhibits the active site of a peroxiredoxin enzyme to amplify redox signalling and the type I interferon response in macrophages. Paywalled
  4. SNT Gatchaman

    Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition, 2024, Khoramjoo et al.

    Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition Mobin Khoramjoo; Kaiming Wang; Karthik Srinivasan; Mahmoud Gheblawi; Rupasri Mandal; Simon Rousseau; David Wishart; Vinay Prasad; Lawrence Richer; Angela M. Cheung; Gavin Y. Oudit BACKGROUND A subset...
  5. SNT Gatchaman

    Review Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches, 2024, Molnar et al.

    Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches Molnar, Tihamer; Lehoczki, Andrea; Fekete, Monika; Varnai, Reka; Zavori, Laszlo; Erdo-Bonyar, Szabina; Simon, Diana; Berki, Tímea; Csecsei, Peter; Ezer, Erzsebet The COVID-19 pandemic, caused...
    • SNT Gatchaman
    • Thread
    • endothelial dysfunction hungary long covid metabolism mitochondria oxidative stress peroxiredoxin
    • Replies: 2
    • Forum: Long Covid research
  6. SNT Gatchaman

    Can inflammatory plasma proteins predict Long COVID or Fatigue severity after SARS-CoV-2 infection?, 2024, Schmitz et al.

    Can inflammatory plasma proteins predict Long COVID or Fatigue severity after SARS-CoV-2 infection? Schmitz; Freuer; Goßlau; Warm; Hyhlik-Dürr; Linseisen; Meisinger; Kirchberger OBJECTIVES To investigate whether specific immune response plasma proteins can predict an elevated risk of developing...
  7. Dolphin

    Immune cell proteomes of Long COVID patients have functional changes similar to those in ME/Chronic Fatigue Syndrome, 2023, Peppercorn, Tate et al.

    https://www.researchsquare.com/article/rs-3335919/v1 Article Immune cell proteomes of Long COVID patients have functional changes similar to those in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Katie Peppercorn1 Christina D. Edgar1 Torsten Kleffmann1 Warren. P Tate1 Email 1...
    • Dolphin
    • Thread
    • hla hla-dqb1 lc=me/cfs new zealand peroxiredoxin proteomics warren tate
    • Replies: 11
    • Forum: ME/CFS research
  8. Sly Saint

    A SWATH-MS analysis of ME/CFS peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction: Sweetman,Vallings,Tate et al Aug 2020

    A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction https://www.researchsquare.com/article/rs-52172/v1
    • Sly Saint
    • Thread
    • 2020 me/cfs metabolism mitochondria mitochondrial dysfunction paper peroxiredoxin proteomics ros vallings sweetman warren tate
    • Replies: 17
    • Forum: ME/CFS research
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