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nrf2

  1. cassava7
    Thread

    Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of [OTC] and prescription NSAIDs, Eisenstein.., 2022

    Highlights A subset of nonsteroidal anti-inflammatory drugs (NSAIDs) activates NRF2 C151 of the chaperone protein KEAP1 is necessary for NRF2...
    Thread by: cassava7, Oct 26, 2022, 0 replies, in forum: Other health news and research
  2. Andy
    Thread

    Preprint: Type I interferon potentiates metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice, 2020, Lei et al

    Mitochondrial dysfunction is a key driver of inflammatory responses in human disease. However, it remains unclear whether alterations in...
    Thread by: Andy, Oct 9, 2020, 0 replies, in forum: Other health news and research
  3. Andy
    Thread

    Nrf2 deficiency induces skeletal muscle mitochondrial dysfunction: a proteomics/bioinformatics approach, 2020, Willis and Deane

    In mice. Intracellular redox homeostasis is crucial for maintaining healthy skeletal muscle. Substantial redox imbalance due to excess reactive...
    Thread by: Andy, Oct 7, 2020, 0 replies, in forum: Other health news and research
  4. Andy
    Thread

    Mechanistic Insights into the Pathophysiology of CFS/ME: Examining Nrf2 Antioxidant Gene Expression & its Role in Combating Oxidative Stress, ongoing

    Struggling at the moment to find more details about this, if/when I do I'll edit them in here. From...
    Thread by: Andy, Mar 23, 2019, 4 replies, in forum: ME/CFS research
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