neurodegeneration

  1. SNT Gatchaman

    Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease, 2025, Shi et al.

    Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease Shi, Sophia M.; Suh, Ryan J.; Shon, D. Judy; Garcia, Francisco J.; Buff, Josephine K.; Atkins, Micaiah; Li, Lulin; Lu, Nannan; Sun, Bryan; Luo, Jian; To, Ning-Sum; Cheung, Tom H.; McNerney, M. Windy; Heiman, Myriam...
  2. SNT Gatchaman

    Meningeal lymphatics-microglia axis regulates synaptic physiology, 2025, Kim et al.

    Meningeal lymphatics-microglia axis regulates synaptic physiology Kyungdeok Kim; Daviti Abramishvili; Siling Du; Zachary Papadopoulos; Jay Cao; Jasmin Herz; Igor Smirnov; Jean-Leon Thomas; Marco Colonna; Jonathan Kipnis SUMMARY Meningeal lymphatics serve as an outlet for cerebrospinal fluid...
  3. SNT Gatchaman

    The neuroimmune connectome in health and disease, 2025, Wheeler and Quintana

    The neuroimmune connectome in health and disease Wheeler, Michael A.; Quintana, Francisco J. The nervous and immune systems have complementary roles in the adaptation of organisms to environmental changes. However, the mechanisms that mediate crosstalk between the nervous and immune systems...
  4. SNT Gatchaman

    Review Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and related dementia, 2024, Jiang et al.

    Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and related dementia Yang Jiang; Jennifer Neal; Pradoldej Sompol; Görsev Yener; Xianghong Arakaki; Christopher M. Norris; Francesca R. Farina; Agustin Ibanez; Susanna Lopez; Abdulhakim Al-Ezzi; Voyko...
  5. SNT Gatchaman

    Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations, 2024, Argentieri et al.

    Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations Argentieri, M. Austin; Xiao, Sihao; Bennett, Derrick; Winchester, Laura; Nevado-Holgado, Alejo J.; Ghose, Upamanyu; Albukhari, Ashwag; Yao, Pang; Mazidi, Mohsen; Lv, Jun; Millwood, Iona; Fry...
  6. Sly Saint

    Experts discover trigger for deadly motor neurone disease

    Experts discover trigger for deadly motor neurone disease (msn.com)
  7. SNT Gatchaman

    SARS-CoV-2 infection causes dopaminergic neuron senescence, 2024, Yang et al.

    SARS-CoV-2 infection causes dopaminergic neuron senescence Liuliu Yang; Tae Wan Kim; Yuling Han; Manoj S. Nair; Oliver Harschnitz; Jiajun Zhu; Pengfei Wang; So Yeon Koo; Lauretta A. Lacko; Vasuretha Chandar; Yaron Bram; Tuo Zhang; Wei Zhang; Feng He; Chendong Pan; Junjie Wu; Yaoxing Huang; Todd...
  8. SNT Gatchaman

    Spatial distributions of white matter hyperintensities on brain MRI: a pooled analysis…, 2023, Coenen et al.

    Spatial distributions of white matter hyperintensities on brain MRI: a pooled analysis of individual participant data from 11 memory clinic cohorts Coenen; Jan Biessels; DeCarli; Fletcher; Maillard; Barkhof; Barnes; Benke; Boomsma; P.L.H. Chen; Dal-Bianco; Dewenter; Duering; Enzinger; Ewers...
  9. SNT Gatchaman

    Review Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics, 2018, Petersen et al.

    Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics Petersen, Mark A.; Ryu, Jae Kyu; Akassoglou, Katerina The blood coagulation protein fibrinogen is deposited in the brain in a wide range of neurological diseases and traumatic injuries with blood–brain barrier (BBB)...
  10. SNT Gatchaman

    Platelet factors attenuate inflammation and rescue cognition in ageing, 2023, Schroer et al.

    Platelet factors attenuate inflammation and rescue cognition in ageing Schroer, Adam B.; Ventura, Patrick B.; Sucharov, Juliana; Misra, Rhea; Chui, M. K. Kirsten; Bieri, Gregor; Horowitz, Alana M.; Smith, Lucas K.; Encabo, Katriel; Tenggara, Imelda; Couthouis, Julien; Gross, Joshua D.; Chan...
  11. rvallee

    Microglial Priming in Infections and Its Risk to Neurodegenerative Diseases, 2022, Maron-Gutierrez et al

    Microglial Priming in Infections and Its Risk to Neurodegenerative Diseases https://www.frontiersin.org/articles/10.3389/fncel.2022.878987/full Infectious diseases of different etiologies have been associated with acute and long-term neurological consequences. The primary cause of these...
  12. Sly Saint

    Alzheimer's and Parkinson's could be halted by a protein that helps hedgehogs hibernate

    Alzheimer's and Parkinson's could be halted by a protein that helps hedgehogs hibernate (msn.com)
  13. SNT Gatchaman

    NIH: Rapid whole-brain high-resolution myelin water fraction mapping from extremely under-sampled MRI data using deep neural network, 2023

    Now published - link here Preprint Rapid whole-brain high-resolution myelin water fraction mapping from extremely under-sampled magnetic resonance imaging data using deep neural network Zhaoyuan Gong, Nikkita Khattar, Matthew Kiely, Curtis Triebswetter, Mustapha Bouhrara Changes in myelination...
  14. SNT Gatchaman

    Life and Death Decisions-The Many Faces of Autophagy in Cell Survival and Cell Death (2022, Yu and Klionsky)

    Life and Death Decisions-The Many Faces of Autophagy in Cell Survival and Cell Death Yu G, Klionsky DJ Autophagy is a process conserved from yeast to humans. Since the discovery of autophagy, its physiological role in cell survival and cell death has been intensively investigated. The inherent...
  15. Andy

    Persistent SARS-CoV-2 Effects Induce Neuropathy Signature in Dorsal Root Ganglia Underlying Hypersensitivity in a Hamster Model, 2022, Serafini et al

    Abstract Post-acute sequelae of COVID-19, commonly known as long-COVID, is defined as a persistent symptom(s) that is unexplainable by alternative diagnosis and lasts beyond three months after the onset of COVID-19. Several studies have now identified long-COVID in >50% of COVID-19 patients...
  16. SNT Gatchaman

    FGF21 attenuates neurodegeneration through modulating neuroinflammation and oxidant-stress, 2020, Kang et al

    FGF21 attenuates neurodegeneration through modulating neuroinflammation and oxidant-stress Kai Kang, Pengfei Xu, Mengxia Wang, Jian Chunyu, Xu Sun, Guiping Ren, Wei Xiao, Deshan Li Previous studies indicate that FGF21 has ability to repair nerve injury, but the specific mechanism is less...
  17. MyalgicE

    Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate (2019) Hunt et al

    Abstract Mitochondrial stress contributes to a range of neurological diseases. Mitonuclear signaling pathways triggered by mitochondrial stress remodel cellular physiology and metabolism. How these signaling mechanisms contribute to neuronal dysfunction and disease is poorly understood. We find...
  18. pteropus

    Can the Flu and Other Viruses Cause Neurodegeneration?

    https://www.the-scientist.com/features/can-the-flu-and-other-viruses-cause-neurodegeneration--65498 also highlights via Amy Proal on Twitter:
  19. leokitten

    Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease (2019) Preische, et al.

    Might increased serum NfL also be a potential biomarker for ME/CFS since it is for Alzheimer’s and other neurological disorders? https://www.nature.com/articles/s41591-018-0304-3
  20. M

    ALS

    https://www.washingtonpost.com/news/national/wp/2018/06/13/feature/devastated-by-als-trying-to-save-others/?noredirect=on&utm_term=.65cc16c53602&wpisrc=nl_rainbow&wpmm=1
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