neopterin

  1. Hutan

    Neopterin

    Petrichor noted here A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff that some papers have reported elevated levels of neopterin in ME/CFS. That's interesting because macrophages produce neopterin when stimulated with...
  2. SNT Gatchaman

    Preprint Systemic Multi-Omics … Reveals Interferon Response Heterogeneity & Links Lipid Metabolism to Immune Alterations in Severe COVID, 2025, Lira-Junior+

    Systemic Multi-Omics Analysis Reveals Interferon Response Heterogeneity and Links Lipid Metabolism to Immune Alterations in Severe COVID-19 Ronaldo Lira-Junior; Anoop Ambikan; Axel Cederholm; Ssefanit Rezene; Flora Mikaeloff; Sara Svensson Akusjarvi; Ahmet Yalcinkaya; Xi Chen; Maike Sperk...
    • SNT Gatchaman
    • Thread
    • amino acids immunometabolic innate immune response interferon interferon-stimulated genes lipids metabolomics mitochondria monocytes neopterin neutrophils plasmalogen proteomics sphingolipids tryptophan
    • Replies: 1
    • Forum: Long Covid research
  3. Andy

    Central and peripheral kynurenine pathway metabolites in COVID-19: Implications for neurological and immunological responses, 2024, Erhardt et al

    Highlights This study represents a pioneering effort by unveiling the elevation of kynurenine pathway metabolites in the CSF of patients with acute COVID-19. The kynurenine pathway is substantially activated in the peripheral system of patients with acute COVID-19. Peripheral...
  4. Hutan

    Analysis of tryptophan metabolites ... in human and murine tissue ... using high resolution mass spectroscopy, 2024, Abuirais, Bergquist et al

    Analysis of tryptophan metabolites and related compounds in human and murine tissue: development and validation of a quantitative and semi-quantitative method using high resolution mass spectrometry Sandy Abujrais, ab S. J. Kumari A. Ubhayasekera ab and Jonas Bergquist *ab Abstract...
  5. SNT Gatchaman

    Epstein-Barr virus reactivation is not causative for post-COVID-19-syndrome in individuals with asymptomatic or mild disease course, 2023, Hoeggerl+

    Epstein-Barr virus reactivation is not causative for post-COVID-19-syndrome in individuals with asymptomatic or mild SARS-CoV-2 disease course Hoeggerl, Alexandra Domnica; Nunhofer, Verena; Lauth, Wanda; Badstuber, Natalie; Held, Nina; Zimmermann, Georg; Grabmer, Christoph; Weidner, Lisa...
  6. E

    Self-Reported Neuropsychiatric Post–COVID-19 Condition and CSF Markers of Neuroinflammation, 2023, McAlpine et al

    Self-Reported Neuropsychiatric Post–COVID-19 Condition and CSF Markers of Neuroinflammation Introduction Long COVID, also known as post–COVID-19 condition (PCC), refers to a range of symptoms that may persist for weeks to months after acute COVID-19. A subset of people with PCC report...
  7. Andy

    Positive Effects of Probiotic Therapy in Patients with Post-Infectious Fatigue, 2023, Obermoser et al

    Abstract Post-infectious fatigue is a common complication that can lead to decreased physical efficiency, depression, and impaired quality of life. Dysbiosis of the gut microbiota has been proposed as a contributing factor, as the gut–brain axis plays an important role in regulating physical...
  8. Hutan

    Increased IgA responses to .. LPS of commensal bacteria .. associated with inflammation, activation of cell-mediated immunity in CFS, 2012, Maes et al

    An old paper, but potentially of interest given a recent finding of increased IgA in a substantial proportion of people attending a post-Covid clinic. Abstract Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is accompanied by a) systemic IgA/IgM responses against the...
  9. Snow Leopard

    Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19, 2022, Huffman et al.

    Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19 Jennifer E. Huffman, Guillaume Butler-Laporte, Atlas Khan, Erola Pairo-Castineira, Theodore G. Drivas, Gina M. Peloso, Tomoko Nakanishi, COVID-19 Host Genetics Initiative, Andrea Ganna, Anurag Verma, J. Kenneth...
  10. Andy

    Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients..., 2021, Holmes et al

    Full title: Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome Abstract We present a multivariate metabotyping approach to assess the functional recovery of nonhospitalized...
  11. Kalliope

    Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses, 2021, Lawlor

    Medical Express Long COVID affecting more than half of patients six months on This is the study the article is about. Way above my head.. Journal of proteome research: Systemic Pertubations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine...
  12. Andy

    Assessment of neopterin and indoleamine 2,3‐dioxygenase activity in patients with seasonal influenza: A pilot study, 2019, Bellmann-Weiler et al

    Open access at https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12677
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