muscle

Abstract: Patients with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suffer from a reduced exercise capacity, skeletal muscle abnormalities and post-exertional malaise (PEM), where symptoms worsen with cognitive or physical exertion. PEM often results in avoidance...

Abstract Mitochondria are essential in supplying energy to skeletal muscle. Near-infrared spectroscopy (NIRS) was developed to noninvasively assess mitochondrial capacity (mV̇O2max) as a rate constant of metabolic recovery after exercise. Purpose This study measured the time course mV̇O2max...

ABSTRACT Background Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In a 2021 review article on the pathophysiology of ME/CFS, we postulated that hypoperfusion and ischemia can result in...

Daily blood flow restriction does not affect muscle fiber capillarization and satellite cell content during two weeks of bed rest in healthy young men Thorben Aussieker; Cas J. Fuchs; Antoine Zorenc; Lex B. Verdijk; Luc J.C. van Loon; Tim Snijders The present study assessed whether single-leg...

Lipid storage myopathy associated with sertraline treatment is an acquired mitochondrial disorder with respiratory chain deficiency Hedberg-Oldfors, Carola; Lindgren, Ulrika; Visuttijai, Kittichate; Shen, Yan; Ilinca, Andreea; Nordström, Sara; Lindberg, Christopher; Oldfors, Anders Lipid...

KEY POINTS Question: Determine the short- and long-term physical impairments and skeletal muscle cellular changes in survivors of critical COVID. Findings: Survivors of critical COVID have high prevalence of weakness, fatigue, and reduced functional exercise capacity with muscle tissue...

Abstract Sickle cell disease (SCD) is characterized by central (cardiac) and peripheral vascular dysfunctions, significantly diminishing exercise capacity and quality of life. While central cardiopulmonary abnormalities in SCD are known to reduce exercise capacity and quality of life; the impact...

miR-29a-3p, a new myokine orchestrating resistance exercise via coordinated metabolic responses Paola Pinto-Hernandez; Manuel Fernandez-Sanjurjo; Daan Paget; Xurde M Caravia; David Roiz-Valle; Juan Castilla-Silgado; Sergio Diez-Robles; Almudena Coto-Vilcapoma; Pau Gama; Pablo M Garcia-Roves...

MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic MIP-C Paula David; Saptarshi Sinha; Khizer Iqbal; Gabriele De Marco; Sahar Taheri; Ella McLaren; Sheetal Maisuria; Gururaj Arumugakani; Zoe Ash; Catrin Buckley; Lauren Coles; Chamila Hettiarachchi; Emma...

Extreme Tolerance of Extraocular Muscles to Diseases and Aging: Why and How? Titova, Angelina; Nikolaev, Sergey; Bilyalov, Airat; Filatov, Nikita; Brovkin, Sergei; Shestakov, Dmitrii; Khatkov, Igor; Pismennaya, Ekaterina; Bondarev, Vyacheslav; Antyuxina, Margarita; Shagimardanova, Elena...

Disuse-Induced Muscle Fatigue: Facts and Assumptions Sergeeva, Xenia V.; Lvova, Irina D.; Sharlo, Kristina A. Skeletal muscle unloading occurs during a wide range of conditions, from space flight to bed rest. The unloaded muscle undergoes negative functional changes, which include increased...

Recovery of neurophysiological measures in post-COVID fatigue: a 12-month longitudinal follow-up study Maffitt, Natalie J.; Germann, Maria; Baker, Anne M. E.; Baker, Mark R.; Baker, Stuart N.; Soteropoulos, Demetris S. One of the major consequences of the COVID-19 pandemic has been the...

Transcription Profile Analysis of Vastus Lateralis Muscle from Patients with Chronic Fatigue Syndrome T. Pietrangelo; R. Mancinelli; L. Toniolo; G. Montanari; J. Vecchiet; G. Fanò; S. Fulle Chronic fatigue syndrome (CFS) is a disabling condition characterized by unexplained chronic fatigue that...

Muscle Haemodynamics and Oxygen Saturation during Exercise and Recovery in Chronic Fatigue Syndrome Patients Jyotpal Singh, Andy D. Roberts, Michael F. Harrison, Nina H. Leavins, James C. Croll, Bharath Krishnan, Patrick Neary INTRODUCTION Controversy exists in the literature whether or not...

Post-COVID-19 condition: systemic inflammation and low functional exercise capacity de Castro, Gabriela Salim; Gama, Leonardo R.; Ramos, Alexandre Ferreira; Gatti da Silva, Guilherme; Teixeira, Alexandre Abilio de Souza; Cunha-Neto, Edecio; de Souza, Heraldo Possolo; Marie, Suely K.; Talib, Leda...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743676/ Abstract Musculoskeletal pain due to ischemia is present in a variety of clinical conditions including peripheral vascular disease (PVD), sickle cell disease (SCD), complex regional pain syndrome (CRPS), and even fibromyalgia (FM). The...

The use of muscle near-infrared spectroscopy NIRS to assess the aerobic training loads of world-class rowers Andrzej Klusiewicz; Kinga Rębiś; Mariusz Ozimek; Adam Czaplicki The objectives of this study were (1) to characterize the changes in oxygenation derived from muscle near-infrared...

Muscle oxygenation of the paretic and nonparetic legs during and after exercise in chronic stroke: Implications for mobility Elizabeth Whyte; Scott Thomas; Susan Marzolini BACKGROUND Oxygen delivery and demand are reduced in the paretic leg of individuals after stroke. However, it is unknown...

Near-infrared spectroscopy-derived muscle oxygen saturation on a 0% to 100% scale: reliability and validity of the Moxy Monitor Andri Feldmann; Roger W. Schmitz; Daniel Erlacher Near-infrared spectroscopy (NIRS) to monitor muscle oxygen saturation (SmO2) is rapidly expanding into applied sports...

Myalgic encephalomyelitis/chronic fatigue syndrome from current evidence to new diagnostic perspectives through skeletal muscle and metabolic disturbances Tiziana Pietrangelo; Stefano Cagnin; Danilo Bondi; Carmen Santangelo; Lorenzo Marramiero; Cristina Purcaro; Raphael Severino Bonadio; Ester...