lyme disease

Saw this posted from Science Translational Medicine (a reputable journal), and thought it looked exciting. I also note liver involvement - there are some reports of liver issues in some people with ME… Interested to know what people think. Abstract Persistent symptoms after an acute infection...

A pilot study of disulfiram for individuals with persistent symptoms despite prior antibiotic treatment for Lyme disease Mara Kuvaldina, Jessica Preston, Denise McClellan, Martina Pavlicova, Thomas H. Brannagan, Brian A. Fallon [Line breaks added] Introduction In vitro studies report that...

Full title: A comparison of genome-wide association analyses of persistent symptoms after Lyme disease, fibromyalgia, and myalgic encephalomyelitis – chronic fatigue syndrome Annemarie G. Hirsch, Anne E. Justice, Amy Poissant, Cara M. Nordberg, Navya S. Josyula, John Aucott, Alison W. Rebman &...

Article from The Sick Times: Now offline: Government resources about Long COVID as a disability (headline refers to the US government)

CspZ variant–specific interaction with factor H incorporates a metal site to support Lyme borreliae complement evasion Kalvis Brangulis; Valerie Sürth; Ashley L. Marcinkiewicz; Inara Akopjana; Andris Kazaks; Janis Bogans; Alisa Huber; Yi-Pin Lin; Peter Kraiczy Polymorphic microbial immune...

Abstract Background/Objectives: Although eligibility criteria for clinical trials significantly impact study outcomes, these criteria are often established without scientific justification, leading to delayed recruitment, small sample sizes, and limited study generalizability. Persistent Lyme...

Symptoms after Lyme disease: What’s past is prologue Adriana Marques Abstract Protracted fatigue and other symptoms can occur after Lyme disease and other infections, with numerous possible drivers. Studies on posttreatment Lyme disease have been inconclusive, with no confirmed biomarker...

ME/CFS and LC are discussed along with Lyme, as well as PEM. https://www.lymedisease.org/complexities-long-haul/

Advancing understanding of chronic illness following infection and identifying novel biomarkers of Lyme disease and Long COVID The MIT MAESTRO study leverages leading edge technology through collaborations with academic and industry partners. The goal of our study is to investigate why some...

The study: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011243 Findings as summarized in Time: https://time.com/6310027/lyme-disease-genes-severe-disease/? My summary: How sick you get depends on the strain (vs species) of Lyme you're infected with. It's not a...

BACKGROUND. Autoimmune diseases often have strong genetic associations with specific HLA-DR alleles. The synovial lesion in chronic inflammatory forms of arthritis shows marked upregulation of HLA-DR molecules, including in postinfectious Lyme arthritis (LA). However, the identity of...

Posts moved from this thread: The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread Absolutely. The advocacy community commonly argues that chronic Lyme disease is grossly underdiagnosed and is responsible for an...

Miranda Hart (UK comedian) has posted two posts on Instagram about ME/CFS and other chronic illness. 1: 2 (video): https://www.instagram.com/tv/B-XggCGFgmr/?utm_source=ig_web_copy_link She starts talking about chronic illness and ME at about 10 min 30 sec. In the video she shows a lot of...