lyme

Reassessing Chronic Lyme Disease and Post-Treatment Lyme Disease Syndrome as Focal Infections András Lakos, Gyöngyi Nagy, Zoltán Varga, Péter Rásonyi-Kovács, Sándor Hornok [Line breaks added] Abstract The complete clinical spectrum of Lyme borreliosis has been recognized for nearly 50 years...

https://www.theguardian.com/world/2025/sep/28/as-my-daughter-got-sicker-and-sicker-our-quest-for-answers-dragged-on-how-did-we-all-miss-the-bacteria-taking-over-her-body Another ill-informed Guardian piece. Milly seems to have ended up with a Lyme diagnosis having been failed by an NHS that...

full article https://www.mirror.co.uk/news/health/ukhsa-issues-alert-anyone-spending-35653424

https://www.msn.com/en-gb/health/other/ai-powered-blood-test-improves-early-lyme-disease-detection/ar-AA1Js1DX?ocid=msedgntp&pc=U531&cvid=ccfa60ba87e943c48c947943ee287984&ei=150

New antibiotic offers hope for more effective Lyme disease treatment

Saw this posted from Science Translational Medicine (a reputable journal), and thought it looked exciting. I also note liver involvement - there are some reports of liver issues in some people with ME… Interested to know what people think. Abstract Persistent symptoms after an acute infection...

Abstract Background/Objectives: Although eligibility criteria for clinical trials significantly impact study outcomes, these criteria are often established without scientific justification, leading to delayed recruitment, small sample sizes, and limited study generalizability. Persistent Lyme...

A Wiltshire man has described "the brutal, brutal environment" he's dealing with during an Atlantic rowing challenge. John Watling, from Lacock, is part of a team attempting what's been dubbed ‘the world's toughest row’ - from the Canaries to Antigua... ...The team is raising money for Lyme...

ME/CFS and LC are discussed along with Lyme, as well as PEM. https://www.lymedisease.org/complexities-long-haul/

Abstract Introduction Diagnosing Borrelia miyamotoi disease (BMD) presents challenges due to its overlap with Lyme disease (LD) symptoms and the lack of reliable laboratory diagnostics. This case study demonstrates the successful use of phage-based PCR (phb-PCR) in identifying B. miyamotoi in...

Another PET TSPO neuroimaging study suggesting neuroinflammation involving microglia, this time in PTLDS: https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-018-1381-4

Abstract Innate immunity, the first line of defense against pathogens, relies on efficient elimination of invading agents by phagocytes. In the co-evolution of host and pathogen, pathogens developed mechanisms to dampen and evade phagocytic clearance. Here, we report that bacterial pathogens...

Summary Background Patients treated for Lyme borreliosis (LB) frequently report persistent symptoms. Little is known about risk factors and etiology. Methods In a prospective observational cohort study with a follow-up of one year, we assessed a range of microbiological, immunological, genetic...

The study: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011243 Findings as summarized in Time: https://time.com/6310027/lyme-disease-genes-severe-disease/? My summary: How sick you get depends on the strain (vs species) of Lyme you're infected with. It's not a...

https://www.pressherald.com/2023/08/31/commentary-the-pandemic-that-coronavirus-uncovered/ (Possibly promoting the writers 'blood test' to identify Lyme or LC.)

Independent: Clinics ‘cash in’ by wrongly diagnosing disease Justin Bieber suffers from (Lyme) https://www.independent.co.uk/news/uk/home-news/bieber-bella-hadid-lyme-disease-symptoms-b2400985.html

NIH awards will fund Post-Treatment Lyme Disease Syndrome research | National Institutes of Health (NIH)

Toward a Common Research Agenda in Infection-Associated Chronic Illnesses: A Workshop to Examine Common, Overlapping Clinical and Biological Factors The National Academies of Sciences, Engineering, and Medicine The two-day event will be held June 29 and 30 in Washington DC. You can also attend...

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(22)00375-5 Highlights • RNA-seq of PBMCs from 152 individuals with post-treatment Lyme disease • Differential expression between acute, post-treatment, and uninfected • Machine learning to identify most relevant genes • 35 genes...

Protein biomarker profiles in serum and CSF in 158 patients with PTLDS or persistent symptoms after presumed tick-bite exposure compared to those in patients with confirmed acute neuroborreliosis Abstract Background Current diagnostics for patients with lingering symptoms categorized as...