Full title:
Immune Signatures in Post-Acute Sequelae of COVID-19 (PASC) and Myalgia/Chronic Fatigue Syndrome (ME/CFS): Insights from the Fecal Microbiome and Serum Cytokine Profiles
Abstract
While there are many postulates for the etiology of post-viral chronic fatigue and other...
Awe reduces depressive symptoms and improves well-being in a randomized-controlled clinical trial
https://www.nature.com/articles/s41598-025-96555-w
Emerging evidence suggests that experiences of awe benefit health and well-being. The present investigation examined the efficacy of an awe...
Integrative Bioinformatics Analysis Identifies Peripheral Blood Hub Genes and Establishes a Five-Gene Diagnostic Model for Long COVID
Yang Liu, Yuwei Shen, Peilian Cao, Yuqiang Qian, Yutong Chen, Daxing Jiang, Jianan Li
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Background
Long COVID (LC) is a multisystem condition...
Effect of normobaric and hyperbaric hyperoxia treatment on symptoms and cognitive capacities in Long COVID patients: a randomised placebo-controlled, prospective, double-blind trial
Leen D’hoore, Peter Germonpré, Bert Rinia, Leonard Caeyers, Nancy Stevens, Costantino Balestra
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Now published. See post #35.
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There Is No Established Connection Between Long-COVID and Chronic Fatigue Syndrome
https://www.preprints.org/manuscript/202506.2016/v1
Abstract
Fatigue is the most common symptom of Long-COVID (LC), characterized by...
I wasn't sure where to put the news about this group's July 9 webinar. So I created a new thread for the Patient-Led Research Fund organization. Please move this post if it belongs elsewhere.
Website for Patient-Led Research Collaborative
Linktree for Patient-Led Research Collaborative...
[68Ga]FAPI PET/CT reveals increased pulmonary fibroblast activation protein expression in long COVID patients after ICU discharge
B. van Leer, M. Londema, Ö. Kasalak, J. H. van Snick, M. L. Duiverman, J. C. Kuijvenhoven, M. D. de Kruif, D. E. Oprea-Lager, K. Pabst, M. E. Hellemons, H. H...
RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine
Drug: Ibudilast
10mg pills, 2 pills twice per day
Other Names:
Drug: Pentoxifylline
400mg pill 3 times per day
Other: Placebo
Placebo matching ibudilast, 2 pills twice per day OR placebo matching...
P109 Circulating autoantibodies targeting G-protein-coupled neurotransmitter receptors: reliable biomarkers for long COVID diagnosis?
M Camici, M Franco, L Talamanca, E Cimini, E Tartaglia, S Notari, M Petino, L Scarnecchia, A Vergori, R Baldelli, P Zuppi, A Antinori
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8: How Stigma Emerges and Mutates: The Case of Long COVID Stigma
Hannah Farrimond, Mike Michael
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Introduction
How do new stigmas emerge? How do they relate to existing stigma? Why are we seeing an emergent devaluation and discrimination of people who have long COVID, given...
Abstract
Mitochondrial disease incorporates a group of rare conditions with no approved treatment to date, except for Leber hereditary optic neuropathy. Therapeutic options to alleviate the symptoms of mitochondrial disease are urgently needed. Sonlicromanol is a promising candidate, as it...
Effectiveness of Treating Post-COVID-19 Conditions (Long COVID) With the SARS-CoV-2 Specific Monoclonal Antibody, Sipavibart
Brief Summary
This placebo-controlled, randomized, blinded, two-arm phase II study will test the safety and potential efficacy of the targeted mAb, Sipavibart (formerly...
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients
Toka Elboraay, Mahmoud A. Ebada, Maged Elsayed, Heba Ahmed Aboeldahab, Hazem Mohamed Salamah, Omar Rageh, Mohamed Elmallahy, Hadeer Elsaeed AboElfarh, Lena Said Mansour...
The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome
Don L. Goldenberg
Introduction
Long COVID is a condition characterized by persistent unexplained symptoms following COVID-19 infection. These symptoms are not related to...
Postacute Sequelae of COVID-19 Across 12 Major Health Domains and 141 Diseases in Individuals With Mental Illness Among COVID-19 Survivors: A Population-Based Cohort Study in South Korea
Jiseung Kang, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Guillaume Fond, Laurent Boyer, Masoud Rahmati, Hayeon...
Executive Function Decline and Its Association With TNF-α in the Later Stages of Post-Acute Sequelae of COVID
Aditi Varenya, K. Vijayalakshmi, Mythri Rajeswara Babu
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Abstract
Beyond the immediate impact of the COVID-19 pandemic, survivors often grapple with incapacitating...
Employers’ Long Game for Long Covid
Scott Conard, Mark Cunningham-Hill, Mohannad Kusti, , Suresh Mukherji, Wayne Rawlins, Stan Schwartz, and Co-authored by members of the National Alliance of Healthcare Purchaser Coalitions’ Medical Director Advisory Council
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In-Brief
The...
https://academic.oup.com/ofid/article/12/6/ofaf278/8154758
Journal Article
Association of SARS-CoV-2 With Health-related Quality of Life 1 Year After Illness Using Latent Transition Analysis
Lauren E Wisk , Michael Gottlieb , Peizheng Chen , Huihui Yu , Kelli N O’Laughlin , Kari A Stephens ...
Long-COVID is associated with increased absenteeism from work
Jaewhan Kim, Sanghoon Lee, Peter Weir
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Abstract
Long-COVID, defined as COVID-19 symptoms persisting for more than 3 months, may lead to persistent health issues requiring extensive medical care. Despite its...
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