long covid

A quest to manage CYP with ME/CFS and long covid under one MDT service – evaluation of a regional centre for CYP ME/CFS and long covid services Abstract Objectives Long Covid (LC) is a debilitating condition seen both in adults and CYP since COVID-19 pandemic.1 The similarities between LC and...

Modifiable lifestyle factors and the risk of post-COVID-19 multisystem sequelae, hospitalization, and death Wang, Yunhe; Su, Binbin; Alcalde-Herraiz, Marta; Barclay, Nicola L.; Tian, Yaohua; Li, Chunxiao; Wareham, Nicholas J.; Paredes, Roger; Xie, Junqing; Prieto-Alhambra, Daniel Effective...

Abstract Background: The term “Long COVID” is commonly used to describe persisting symptoms after acute COVID‑19. Until now, proposed mechanisms for the explanation of Long COVID have not related quantitative measurements to basic laws. In this work, a common framework for the Long COVID...

Abstract Long COVID is a common sequela of SARS-CoV-2 infection. Data from numerous scientific studies indicate that long COVID involves a complex interaction between pathophysiological processes. Long COVID may involve the development of new diagnosable health conditions and exacerbation of...

Influential studies from the VA St. Louis take a broad view of long Covid. Not every expert agrees with the approach. https://undark.org/2024/07/25/long-covid-clash-of-definition-study-design/

Identification of SARS-CoV-2 Persistent Infectious Epithelial Syndrome (SPIES) as a Novel Disease Entity using Clinical, Histologic, and RNA Programmatic Data Thomas Wallach, Ahmed Soliman, John Agboola, Shagun Sharma, Lais Araujo Coelho, Meredith Pittman, Christos Chatzinakos, Sergios-Orestis...

Key Points Question Does prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)–like illness differ between individuals with an acute infection–like index illness who are COVID-19 positive or negative? Findings In this cohort study of 4378 participants, the weighted...

Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome Maiti, Amit K. Long or Post COVID-19 is a condition of collected symptoms persisted after recovery from COVID-19. Host genetic factors play a crucial role in developing Long...

Abstract SARS-CoV-2-contributes to sickness and death in COVID-19 patients partly by inducing a hyper-proinflammatory immune response in the host airway. This hyper-proinflammatory state involves activation of signaling by NFκB, and unexpectedly, ENaC, the epithelial sodium channel...

Brief Summary The trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants with Long Covid compared to placebo. Viral infection and viral reactivation have been documented in Long Covid. Participants will be randomly allocated to receive antivirals, TDF...

Sleep and circadian rhythm alterations in myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID fatigue syndrome and its association with cardiovascular risk factors: A prospective cohort study Abstract This study aimed to investigate circadian rhythm manifestations in Myalgic...

A Long COVID Definition A Chronic, Systemic Disease State with Profound Consequences (Consensus Study Report) National Academies of Sciences, Engineering, and Medicine. 2024. A Long COVID Definition: A Chronic, Systemic Disease State with Profound Consequences. Washington, DC: The National...

Prevalence, risk factors, and impact of long COVID in a socially vulnerable community in Brazil: a prospective cohort study Summary Background Long COVID is an emerging global public health issue. Socially vulnerable communities in low- and-middle-income countries were severely impacted by the...

Physical exercise-related manifestations of long COVID: A systematic review and meta-analysis Zheng; Chen; Dai; Wan; Sun; Huang; Chen OBJECTIVES This study aims to systematically assess physical exercise-related symptoms of post-acute sequelae of SARS-CoV-2 infection (PASC or long COVID) in...

New-onset Parkinsonism as a Covid-19 infection sequela: A systematic review and meta-analysis Published online 8 Aug 2022 Syed Sami Ali, Afshan Mumtaz, Mohammad Aadil Qamar, Sameer Saleem Tebha, Azma Parhin, Mehwish Butt, Mohammad Yasir Essare Background There remains a scarcity of literature...

Full title: Inflammatory profiles are associated with long COVID up to 6 months after COVID-19 onset: A prospective cohort study of individuals with mild to critical COVID-19 Abstract Background: After initial COVID-19, immune dysregulation may persist and drive post-acute sequelae of COVID-19...

The efficacy of antivirals, corticosteroids, and mAbs as acute COVID treatments in reducing the incidence of long COVID: a Systematic Review and meta-analysis Gangqiang Sun, Ke Lin, Jingwen Ai, Wenhong Zhang Abstract Background: Whether treatment during acute COVID results in protective...

Camille A. Broussard, MD, MPHa,*, Alba Azola, MDb,c, Peter C. Rowe, MDd Pediatric Clinics of North America (2024) Post-acute sequelae of SARS CoV-2 infection (PASC) in adolescents and young adults (AYAs) presents heterogeneously, often with multisystem involvement. Between 3 and 6 months...

Post–Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2 After Infection During Pregnancy Metz, Torri D.; Reeder, Harrison T.; Clifton, Rebecca G.; Flaherman, Valerie; Aragon, Leyna V.; Baucom, Leah Castro; Beamon, Carmen J.; Braverman, Alexis; Brown, Jeanette; Cao...

Insights from an N3C RECOVER EHR-based cohort study characterizing SARS-CoV-2 reinfections and Long COVID Hadley, Emily; Yoo, Yun Jae; Patel, Saaya; Zhou, Andrea; Laraway, Bryan; Wong, Rachel; Preiss, Alexander; Chew, Rob; Davis, Hannah; Brannock, M. Daniel; Chute, Christopher G.; Pfaff, Emily...