Abstract The causes of depression are diverse and are still not fully understood. Recently, an increasing role is attributed to nutritional and...
I present here a comparison between the levels of tryptophan (Trp), kynurenine (Kyn), serotonin (Ser), Kyn/Trp, and Ser/Trp in cerebrospinal fluid...
Aussie breakthrough on the long Covid condition that leaves sufferers with symptoms similar to 'traumatic brain injury (Daily Mail - no really)...
Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, complex, and highly debilitating long-term illness. People...
Tryptophan and the innate intestinal immunity: Crosstalk between metabolites, host innate immune cells, and microbiota Yunke Li, Ning Liu, Yao Ge,...
Abstract Background The tryptophan–kynurenine–nicotinamide adenine dinucleotide (oxidized; NAD+) pathway is closely associated with regulation of...
Zika virus (ZIKV) is an arbovirus belonging to Flaviviridae family that emerged as a global health threat due to its association with microcephaly...
Abstract Chronic stress is associated with an increased conversion of tryptophan (TRP) into kynurenine (KYN). However, only a few studies...
Abstract The kynurenine pathway (KP) is the main path for tryptophan metabolism, and it represents a multitude of potential sites for drug...
Full title: Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase...
Neurodegenerative diseases are multifactorial, initiated by a series of the causative complex which develops into a certain clinical picture. The...
Abstract The importance of tryptophan as a precursor for neuroactive compounds has long been acknowledged. The metabolism of tryptophan along the...
Both red blood cells damage and kynurine identified in LongCovid research...
https://lupus.bmj.com/content/5/1/e000254 Conclusions Metabolites in the kynurenine pathway are altered in patients with SLE compared with...
https://journals.sagepub.com/doi/full/10.1177/1178646920936279 Central fatigue leads to reduced ability to perform mental tasks, disrupted social...
Full title: Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the...
STUDY AIM The purpose of the study is to evaluate whether kynurenine is directly connected to ME/CFS patient symptom severity. LEAD INVESTIGATORS...
Reprogramming of host metabolism supports viral pathogenesis by fueling viral proliferation, by providing, for example, free amino acids and fatty...
Full title: Increased Expression of Indoleamine 2,3-Dioxygenase (IDO) in Vogt-Koyanagi-Harada (VKH) Disease May Lead to a Shift of T Cell...
From their May Momentum 2020 newsletter & https://www.omf.ngo/maymomentum/ We are announcing THREE major research projects throughout May! [...]...
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