jak inhibitors

  1. forestglip

    Favorable responses to upadacitinib, a JAK1 inhibitor, in [LC] with predominant neuropsychiatric symptoms: case reports [...], 2025, Jyonouchi et al

    Favorable responses to upadacitinib, a JAK1 inhibitor, in long COVID patients with predominant neuropsychiatric symptoms: case reports in 2 autistic patients and one typically developing patient Harumi Jyonouchi, Jeffery Kornitzer, Lee Geng [Line breaks added] Abstract The long-term impact of...
    • forestglip
    • Thread
    • autism jak inhibitors jak1 long covid neuropsychiatric disorders upadacitinib
    • Replies: 2
    • Forum: Long Covid research
  2. pooriepoor91

    Potential Mechanism of Fatigue Induction and Its Management by JAK Inhibitors in Inflammatory Rheumatic Diseases 2024, Anna Felis-Giemza et al

    Open Access: Full article: Potential Mechanism of Fatigue Induction and Its Management by JAK Inhibitors in Inflammatory Rheumatic Diseases (tandfonline.com) Abstract It is well known that fatigue is a highly disabling symptom commonly observed in inflammatory rheumatic diseases (IRDs)...
  3. SNT Gatchaman

    Preprint BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III, 2024, Chen et al

    BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III Brandon Chen; Theophilus M Lynn-Nguyen; Pankaj Jadhav; Benjamin S Halligan; Nicholas J Rossiter; Rachel M Guerra; Sergei Koshkin; Imhoi Koo; Pietro Morlacchi...
    • SNT Gatchaman
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    • brd4 complex 3 endoplasmic reticulum epigenetics hif-1 hypoxia integrated stress response jak inhibitors jak-stat mitochondria mitochondrial dynamics perk
    • Replies: 0
    • Forum: Other health news and research
  4. E

    Protocol REVERSE-Long COVID-19 With Baricitinib Study (REVERSE-LC)

    REVERSE-Long COVID-19 With Baricitinib Study (REVERSE-LC) The largest study on Long-Covid initiated by Wes Ely is starting in the upcoming months. In this large (n=550) Randomized, placebo-controlled, double-blind, parallel-design superiority design Phase 3 trial for Long-Covid 4 mg of...
  5. SNT Gatchaman

    Preprint Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19, 2024, Ashok et al.

    Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19 Deepthi Ashok; Ting Liu; Joseph Criscione; Meghana Prakash; Byunggik Kim; Julian Chow; Morgan Craney; Kyriakos Papanicolaou; Agnieszka Sidor; D. Brian Foster; Andrew Pekosz...
    • SNT Gatchaman
    • Thread
    • arrhythmia cardiac cardiac function cytokines innate immune response interferon interferon-stimulated genes jak inhibitors jak-stat macrophages mitochondria reactive oxygen species
    • Replies: 0
    • Forum: Long Covid research
  6. SNT Gatchaman

    Review The JAK/STAT signaling pathway: from bench to clinic, 2021, Hu et al.

    The JAK/STAT signaling pathway: from bench to clinic Hu, Xiaoyi; li, Jing; Fu, Maorong; Zhao, Xia; Wang, Wei The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular...
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