Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA PAX LC: a double-blind, randomised, placebo-controlled, phase 2, decentralised trial
Mitsuaki Sawano; Bornali Bhattacharjee; César Caraballo; Rohan Khera; Shu-Xia Li; Jeph Herrin; Dany Christian; Andreas...
Abstract
COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the population reports a chronic debilitating condition after COVID-19 vaccination, often referred to as post- vaccination syndrome (PVS). To explore potential pathobiological features associated with...
Abstract:
Background: Complex chronic conditions like Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome involve energy limitations and changes in heart rate variability (HRV) and resting heart rate (HR). Mobile health technologies now offer real-time, valid measurements of HRV...
A causal link between autoantibodies and neurological symptoms in long COVID
Abstract
Acute SARS-CoV-2 infection triggers the generation of diverse and functional autoantibodies (AABs), even after mild cases. Persistently elevated autoantibodies have been found in some individuals with long...
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Abstract
SARS-CoV-2 infection can result in the development of a constellation of persistent sequelae following acute disease called post-acute sequelae of COVID-19 (PASC) or Long COVID. Individuals diagnosed with Long COVID frequently report unremitting fatigue, post-exertional malaise, and a...
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Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain
Preprint Abstract
Survivors of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection frequently experience lingering neurological symptoms, including impairment in...
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