Full title:
The Effect on Quality of Life of Therapeutic Plasmapheresis and Intravenous Immunoglobulins on a Population of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients with Elevated β-Adrenergic and M3-Muscarinic Receptor Antibodies—A Pilot Study...
Effect on Quality of Life of Therapeutic Plasmapheresis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients with Elevated β-Adrenergic and M3-Muscarinic Receptor Antibodies – a Pilot Study
Boglárka Oesch-Régeni, Nicolas Germann, Georg Hafer, Dagmar Schmid, Norbert Arn
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Abstract
Objective
Although SARS-CoV-2 primarily targets the respiratory system, there is evidence that it can also infect the central nervous system, especially in children, leading to neurological symptoms and long-term consequences. It is imperative to summarize the possible mechanisms, main...
Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies
Cole Maguire; Kristina Kashyap; Elizabeth Williams; Aziz Rija; Maisey Schuler; Cheyenne Ahamed; Chumeng Wang; Aurelia Mena; Jeffrey Saniuk; Johanna Busch; Sara Austin; Mary Kelley...
My son, 13, with Long Covid and polyneuropathy has been receiving intensive immunoglobulin infusion therapy (IVIG) since January 25.
Previously Bell 10 for a year, now within 2 months it has risen to Bell 50, and the trend is rising.
PEM almost no longer exists.
He can hardly believe his luck -...
Full title: A review of intravenous immunoglobulin in the treatment of neuroimmune conditions, acute COVID-19 infection, and post-acute sequelae of COVID-19 Syndrome
Highlights
IVIG has demonstrated efficacy in over 100 disorders, spanning hematologic, inflammatory, autoimmune, and infectious...
Autoimmunity in Syndromes of Orthostatic Intolerance: An Updated Review
Pena, Clarissa; Moustafa, Abdelmoniem; Mohamed, Abdel-Rhman; Grubb, Blair
Orthostatic intolerance is a broad term that represents a spectrum of dysautonomic disorders, including postural orthostatic tachycardia syndrome...
Abstract
Objective: This study assesses response to intravenous immunoglobulin (IVIG) in presumed autoimmune postural orthostatic tachycardia syndrome (POTS).
Background: POTS may be associated with autoimmune disorders, serum autoantibodies, or recent infection. Uncontrolled case studies...
Objectives: Pediatric acute-onset neuropsychiatric syndrome (PANS) is characterized by an abrupt-onset of severe psychiatric symptoms including OCD, anxiety, cognitive difficulties, and sleep issues which is thought to be a post-infection brain inflammatory disorder. We observed postural...
Abstract
The findings of controlled trials on use of intravenous immunoglobulin G (IV IgG) to treat myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are generally viewed as representing mixed results. On detailed review, a clearer picture emerges, which suggests that the potential...
Highlights
• ME/CFS is characterized by skewed B cell receptor gene usage.
• Upregulation of specific IGHV genes correlated to infection-related episodes at onset.
• Plasmablasts of ME/CFS patients upregulated interferon response genes.
• B cell receptor repertoire analysis can provide a useful...
Abstract
A patient with severe postural orthostatic tachycardia syndrome (POTS) and mast cell activation syndrome (MCAS) received immunotherapy with low-dose naltrexone (LDN) and intravenous immunoglobulin (IVIg) and antibiotic therapy for small intestinal bacterial overgrowth (SIBO). A dramatic...
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