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itaconate

  1. SNT Gatchaman
    Thread

    Review Defining trained immunity and its role in health and disease, 2020, Netea et al.

    Defining trained immunity and its role in health and disease Netea, Mihai G.; Domínguez-Andrés, Jorge; Barreiro, Luis B.; Chavakis, Triantafyllos;...
    Thread by: SNT Gatchaman, Mar 1, 2024, 6 replies, in forum: Other health news and research
  2. SNT Gatchaman
    Thread

    Preprint Frataxin Deficiency Drives Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering Inflammatory Phenotype in Microglia,2023,Sciarretta+

    Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia...
    Thread by: SNT Gatchaman, Oct 25, 2023, 12 replies, in forum: Other health news and research
  3. darrellpf
    Thread

    TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages, 2022, Schuster et al

    "Successful elimination of bacteria in phagocytes occurs in the phago-lysosomal system, but also depends on mitochondrial pathways. Yet, how these...
    Thread by: darrellpf, Jul 22, 2022, 3 replies, in forum: 'Conditions related to ME/CFS' news and research
  4. SNT Gatchaman
    Thread

    The Emerging Application of Itaconate: Promising Molecular Targets and Therapeutic Opportunities, 2021, Lin et al

    The Emerging Application of Itaconate: Promising Molecular Targets and Therapeutic Opportunities Jiaqi Lin, Jinxuan Ren, Dave Schwinn Gao, Yi Dai,...
    Thread by: SNT Gatchaman, Jul 13, 2022, 0 replies, in forum: Other health news and research
  5. Jaybee00
    Thread

    The itaconate shunt hypothesis

    [MEDIA]
    Thread by: Jaybee00, Jul 12, 2022, 117 replies, in forum: Possible causes and predisposing factor discussion
  6. Andy
    Thread

    Review Article: A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation, 2018, O'Neill et al

    Review article Metabolism in immune cells is no longer thought of as merely a process for adenosine triphosphate (ATP) production, biosynthesis,...
    Thread by: Andy, Mar 11, 2018, 1 replies, in forum: Other health news and research
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