gdf15

  1. SNT Gatchaman

    Preprint Charting the Circulating Proteome in ME/CFS: Cross System Profiling and Mechanistic insights, 2025, Hoel, Fluge, Mella+

    Charting the Circulating Proteome in ME/CFS: Cross System Profiling and Mechanistic insights August Hoel; Fredrik Hoel; Sissel Elisabeth Furesund Dyrstad; Henrique Chapola; Ingrid Gurvin Rekeland; Kristin Risa; Kine Alme; Kari Sorland; Karl Albert Brokstad; Hans-Peter Marti; Olav Mella; Oystein...
    • SNT Gatchaman
    • Thread
    • bone marrow capillaries coagulation complement endothelium ephrin fgf21 fluge gdf15 hif-1 histone hypoxia leptin mcts1 mella myeloperoxidase myoglobin neutrophils pxdn sex differences
    • Replies: 66
    • Forum: ME/CFS research
  2. forestglip

    Review Comparative Metabolomics of Four Fatigue Disorders: [CFS/ME], [LC], Fibromyalgia (FM), and Major Depressive Disorder (MDD), 2024, Kuruvilla et al

    Comparative Metabolomics of Four Fatigue Disorders: Chronic Fatigue Syndrome (CFS/ME), Long COVID, Fibromyalgia (FM), and Major Depressive Disorder (MDD) Heather G Kuruvilla, Colleen Weaver, Joshua Jones, Hunter Tenpas [Poster presentation at Scholars Symposium 2024] Fatigue is a common...
  3. chillier

    Atlas of the plasma proteome in health and disease in 53,026 adults, 2024, Yue-Ting Deng et al

    Link: https://www.cell.com/cell/fulltext/S0092-8674(24)01268-6 Highlights • Construct a comprehensive proteomics atlas for 1,706 human diseases and traits • Machine-learning-based big data uncover promising diagnostic and predictive biomarkers • Identify 37 drug repurposing prospects and 26...
  4. SNT Gatchaman

    Growth Differentiation Factor-15 Is Considered a Predictive Biomarker of Long COVID in Non-hospitalized Patients, 2024, Ono et al.

    Growth Differentiation Factor-15 Is Considered a Predictive Biomarker of Long COVID in Non-hospitalized Patients Rie Ono; Shin Takayama; Michiaki Abe; Ryutaro Arita; Takaaki Abe; Tadashi Ishii; Rie Ono; Shin Takayama Sr.; Michiaki Abe; Ryutaro Arita; Takaaki Abe; Tadashi Ishii Mitochondrial...
  5. Andy

    Preprint The Energetic Stress Marker GDF15 is Induced by Acute Psychosocial Stress, 2024, Huang et al

    Preprint Psychobiological regulation of plasma and saliva GDF15 dynamics in health and mitochondrial diseases Abstract GDF15 (growth differentiation factor 15) is a marker of cellular energetic stress linked to physical-mental illness, aging, and mortality. However, questions remain about its...
  6. SNT Gatchaman

    Review SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19, 2024, Guarnieri et al.

    SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19 Guarnieri; Haltom; Albrecht; Lie; Olali; Widjaja; Ranshing; Angelin; Murdock; Wallace To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an exhaustive survey of the cellular metabolic...
    • SNT Gatchaman
    • Thread
    • atf6 cgas-sting epigenetics fgf21 gdf15 glycolysis hif-1 histone innate immune system integrated stress response interferon metabolic reprogramming metabolism mitochondria oxidative phosphorylation pentose phospate pathway perk tlr-9 upr
    • Replies: 2
    • Forum: Long Covid research
  7. J

    GDF15 linked to maternal risk of nausea and vomiting during pregnancy 2023 Fejzo et al (hyperemesis gravidarum - morning sickness in pregnancy)

    https://www.nytimes.com/2023/03/14/well/marlena-fejzo-hyperemesis-gravidarum.html?unlocked_article_code=i7exBjGLMkMQVJKOgEZ_PBv29j4GYrj4q6R0YqeSGQumAtqyVKkXwLaZ7KLVZGykBQcxBasbEjYPcILSMlSxNDlw_xrprtr7hB0f7w_NpdqRTRX0ASFJqoJE3nbD1s1ehkYpzQPzcFMspQHlhOMLG0wwGtq1IVxqeaiDdNQ3_Of5T64T45gIEO70aUzvW5kwN...
  8. SNT Gatchaman

    Review Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease, 2023, Boardman, Wüst et al.

    Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease Boardman, Neoma T; Trani, Giulia; Scalabrin, Marco; Romanello, Vanina; Wüst, Rob C I Mitochondria sense both biochemical and energetic input in addition to communicating signals regarding the...
  9. SNT Gatchaman

    Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts, 2023, Guarnieri et al.

    Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts Joseph W. Guarnieri; Joseph M. Dybas; Hossein Fazelinia; Man S. Kim; Justin Frere; Yuanchao Zhang; Yentli Soto Albrecht; Deborah G. Murdock; Alessia Angelin; Larry N. Singh; Scott L. Weiss; Sonja M...
    • SNT Gatchaman
    • Thread
    • covid fgf21 gdf15 glycolysis glyolysis hif-1 integrated stress response long covid mavs metabolism micro-rna mitochondria oxphos
    • Replies: 14
    • Forum: Long Covid research
  10. SNT Gatchaman

    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy, 2023, Southwell et al.

    A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy Nneka Southwell; Guido Primiano; Viraj Nadkarni; Nabeel Attarwala; Emelie Beattie; Dawson Miller; Sumaitaah Alam; Irene Liparulo; Yevgeniya I Shurubor; Maria Lucia Valentino; Valerio Carelli; Serenella...
    • SNT Gatchaman
    • Thread
    • amino acids atf4 fatty acid metabolism fatty acid oxidation fgf21 gdf15 integrated stress response lipid droplets lipid metabolism lipids metabolism mitochondria mtor muscle myopathy tca cycle
    • Replies: 4
    • Forum: Other health news and research
  11. cassava7

    Serum GDF-15 Levels Accurately Differentiate Patients with Primary Mitochondrial Myopathy (…) from Patients with [CFS], Bermejo-Guerrero et al, 2023

    Serum GDF-15 Levels Accurately Differentiate Patients with Primary Mitochondrial Myopathy, Manifesting with Exercise Intolerance and Fatigue, from Patients with Chronic Fatigue Syndrome Authors from the Neuromuscular Disorders Unit of the Hospital Universitario 12 de Octubre in Madrid (national...
    • cassava7
    • Thread
    • differential diagnosis exercise intolerance gdf15 mitochondrial disease mitochondrial myopathy muscle
    • Replies: 4
    • Forum: ME/CFS research
  12. cassava7

    Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of [OTC] and prescription NSAIDs, Eisenstein.., 2022

    Highlights A subset of nonsteroidal anti-inflammatory drugs (NSAIDs) activates NRF2 C151 of the chaperone protein KEAP1 is necessary for NRF2 activation by indomethacin Indomethacin reduces inflammation in endotoxemia and gout models dependent on NRF2 Summary Nonsteroidal...
  13. Andy

    ..defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity.., 2020, Choi et al

    Full title - An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models Paywall, https://link.springer.com/article/10.1007%2Fs00125-019-05082-7 Sci hub, https://sci-hub.se/10.1007/s00125-019-05082-7
  14. Sly Saint

    Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome, 2019, Melvin, Lacerda, Nacul et al

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02153-6 eta: can someone explain the conclusions
    • Sly Saint
    • Thread
    • 2019 blood cellular stress gdf15 lacerda me/cfs melvin nacul paper serum
    • Replies: 11
    • Forum: ME/CFS research
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